61 datasets found
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Federal
Identifying chemicals and mixtures of potential biological concern detected in passive samplers from Great Lakes tributaries using high-throughput data and biological pathways recent views
U.S. Environmental Protection Agency —
Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar... -
Federal
Toward an AOP Network-based tiered testing strategy for the assessment of thyroid hormone disruption recent views
U.S. Environmental Protection Agency —
No novel data were reported in association with this product. This dataset is not publicly accessible because: The associated publication is a review/forum-type... -
Federal
The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish recent views
U.S. Environmental Protection Agency —
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase... -
Federal
Bioactive Contaminants of Emerging Concern in National Park Waters of the Northern Colorado Plateau, USA recent views
U.S. Environmental Protection Agency —
Water and sediment was collected to assess the occurrence of contaminants of emerging concern (CECs) in National Park waters of the northern Colorado Plateau, USA.... -
Federal
Adverse outcome pathway recent views
U.S. Environmental Protection Agency —
cell culture information with toxicity and proteomic changes. This dataset is associated with the following publication: VanEmon, J., P. Pan, and F. Van Breukelen.... -
Federal
Dataset for ORD-033373: Gene Expression Thresholds Are Predictive of Rat Liver Tumorigens in Short-Term Assays recent views
U.S. Environmental Protection Agency —
The microarray experiments used in the study. This dataset is associated with the following publication: Hill, T., J. Rooney, J. Abedini, H. El-Masri, C. Wood, and J.... -
Federal
Integrative computational approaches to inform relative bioaccumulation potential of per- and polyfluoroalkyl substances (PFAS) across species recent views
U.S. Environmental Protection Agency —
Datasets included in the entry are Results from the US Environmental Protection Agency Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool and... -
Federal
SEQUENCING AND DE NOVO DRAFT ASSEMBLIES OF A FATHEAD MINNOW (Pimpehales promelas) reference genome recent views
U.S. Environmental Protection Agency —
The dataset provides the URLs for accessing the genome sequence data and two draft assemblies as well as fathead minnow genotyping data associated with estimating the... -
Federal
In vivo and In vitro neurochemical-based assessments of wastewater effluents from the Maumee River area of concern. recent views
U.S. Environmental Protection Agency —
All primary data reported in this paper were generated by non-federal collaborators from the University of Michigan and McGill University. US EPA-ORD personnel... -
Federal
Larval fathead minnow swim bladder inflation following exposure to 2-mercaptobenzothiazole recent views
U.S. Environmental Protection Agency —
In this study, a hypothesized adverse outcome pathway (AOP) linking inhibition of thyroid peroxidase (TPO) activity to impaired swim bladder inflation was... -
Federal
Putative adverse outcome pathway development based on physiological responses of female fathead minnows to model estrogen versus androgen receptor agonists recent views
U.S. Environmental Protection Agency —
"Morshead ML, Jensen KM, Ankley GT, Vliet S, LaLone CA, Aller AV, Watanabe KH, Villeneuve DL. Putative adverse outcome pathway development based on physiological... -
Federal
Defining the Taxonomic Domain of Applicability for Mammalian-Based High-Throughput Screening Assays recent views
U.S. Environmental Protection Agency —
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins... -
Federal
Adverse Outcome Pathway Networks I: Development and Applications recent views
U.S. Environmental Protection Agency —
In September, 2015, a water sample was collected downstream of a major metropolitan waste water treatment plant that discharges to the South Platte River, Colorado,... -
Federal
Male Fathead Minnow Transcriptomes and Associated Chemical Analytes in Milwaukee Estuary System recent views
U.S. Environmental Protection Agency —
This dataset presents the full hepatic transcriptomes of fathead minnows (Pimephales promelas) caged for four days at multiple sites within the Milwaukee Estuary area... -
Federal
Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid recent views
U.S. Environmental Protection Agency —
The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form,... -
Federal
Conversion of environmental estrone to estradiol by male fathead minnows recent views
U.S. Environmental Protection Agency —
This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations... -
Federal
Dataset for ORD-033344: A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays recent views
U.S. Environmental Protection Agency —
Microarray experiments used in the study. This dataset is associated with the following publication: Corton, J., T. Hill, J. Sutherland, J. Stevens, and J. Rooney. A... -
Federal
Adverse outcome pathway (AOP) development and weight of evidence evaluation as illustrated by ecological case studies using online tools such as ECOTOX and SeqAPASS recent views
U.S. Environmental Protection Agency —
The majority of this dataset includes the query output from online databases ECOTOX and SeqAPASS used to support the ecological AOP case studies described within the... -
Federal
Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes recent views
U.S. Environmental Protection Agency —
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic... -
Federal
A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows recent views
U.S. Environmental Protection Agency —
The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR)...
61 datasets found