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Obstructive sleep apnea and vascular disease
There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as... -
Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports
Background This investigation was undertaken to describe patient perception and awareness of the polycystic ovary syndrome (PCOS), the most common cause of... -
Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysis
Background It is possible that psychopathological differences exist between the restricting and bulimic forms of anorexia nervosa. We investigated localized differences of brain... -
Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment
Background Bariatric patients showing poor "focus" during treatment more often failed to lose weight or maintain reduced weight. Evaluation of these patients identified a number... -
Time course of muscle soreness following different types of exercise
Background Post-exercise muscle soreness is a dull, aching sensation that follows unaccustomed muscular exertion. Primarily on the basis of previous laboratory-based research on... -
Application of the development stages of a cluster randomized trial to a framework for evaluating complex health interventions
Introduction Trials of complex health interventions often pose difficult methodologic challenges. The objective of this paper is to assess the extent to which the various... -
Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling
Background: Ventilator-associated bacterial pneumonia (VAP) is a important intensive care unit (ICU)-acquired infection in mechanically ventilated patients. Early and correct... -
Impact of obesity on glucose and lipid profiles in adolescents at different age groups in relation to adulthood
Background As obesity is rapidly becoming a major medical and public health problem, the aim of our study was to determine: 1) if obesity in Caucasian adolescents at 5 different... -
Oral contraceptive use before first birth and risk of breast cancer: a case control study
Background The aim of this study was first, to investigate whether women starting oral contraceptive (OC) use at a young age and before first birth have an increased risk for... -
A cross-sectional study of early identification of postpartum depression: Implications for primary care providers from The Ontario Mother & Infant Survey
Background This survey's objective was to provide planning information by examining utilization patterns, health outcomes and costs associated with existing practices in the... -
Internet hand x-rays: A comparison of joint space narrowing and erosion scores (Sharp/Genant) of plain versus digitized x-rays in rheumatoid arthritis patients
Background The objective of the study is to examine the reliability of erosion and joint space narrowing scores derived from hand x-rays posted on the Internet compared to... -
Organization specific predictors of job satisfaction: findings from a Canadian multi-site quality of work life cross-sectional survey
Background Organizational features can affect how staff view their quality of work life. Determining staff perceptions about quality of work life is an important consideration... -
The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis
Background Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in multidisciplinary... -
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however case reports... -
Genetic epidemiology: Systemic lupus erythematosus
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine... -
To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?
Background Patients with Alzheimer's disease experience a progressive loss of cognitive function, and the ability to independently perform activities of daily life. Sometimes a... -
How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)
Background The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy starting with... -
Asthma and PM
PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air pollution used... -
The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect the...
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