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Federal
Cancer Incidence - Surveillance, Epidemiology, and End Results (SEER) Registries Limited-Use 55 recent views
U.S. Department of Health & Human Services —
SEER Limited-Use cancer incidence data with associated population data. Geographic areas available are county and SEER registry. The Surveillance, Epidemiology, and... -
Federal
Targeted pathway-based in vivo testing using thyroperoxidase inhibition to evaluate plasma thyroxine as a surrogate metric of metamorphic success in model amphibian Xenopus laevis
U.S. Environmental Protection Agency —
These data are represented in tables and graphs in the article, "Targeted pathway-based in vivo testing using thyroperoxidase inhibition to evaluate plasma thyroxine... -
Federal
Dataset_1: data in figures. Dataset_2: SI_Tables.
U.S. Environmental Protection Agency —
Dataset for the publication "Expanded High-Throughput Screening and Chemotype-Enrichment Analysis of the Phase II:e1k ToxCast Library for Human Sodium-Iodide... -
Federal
Iodotyrosine deiodinase: mRNA expression and experimental inhibition study in Xenopus laevis
U.S. Environmental Protection Agency —
This excel file contains the resultant data from a study on iodotyrosine deiodinase in the model amphibian species, Xenopus laevis. These data include: tadpole growth... -
Federal
Gestational Exposure to Perchlorate in the rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain
U.S. Environmental Protection Agency —
This dataset contains results from rodent study. Thyroid hormones and brain endpoints are reported for pregnant rat dams and progeny on gestational day 20 following... -
Federal
Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats
U.S. Environmental Protection Agency —
behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil. Electrophysiological... -
Federal
Fetal and Postnatal Cortical Thyroid Hormone Levels and Bioindicators
U.S. Environmental Protection Agency —
thyroid hormones in serum and in brain were measured in fetal and neonatal rat cortex after graded levels of a thyroid hormone synthesis inhibitor were administered... -
Federal
Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines
U.S. Environmental Protection Agency —
Biomarker Image Cytometry. The cell-level frequency of NK2 Homeobox 1 (NKX2-1), Keratin 7 (KRT7), and Thyroglobulin (TG) protein staining were quantitatively... -
Federal
Doc Title: Adult Hippocampal Neurogenesis is Impaired by Transient Developmental Thyroid Hormone Disruption
U.S. Environmental Protection Agency —
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis... -
Federal
Secondary screening method for sodium-iodide symporter inhibition utilizing FRTL-5 cells data set
U.S. Environmental Protection Agency —
Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. This dataset is... -
Federal
Effects of Chronic Exposure to Triclosan on Reproductive and Thyroid Endpoints in the Adult Wistar Female Rat
U.S. Environmental Protection Agency —
This dataset includes the results of a long term adult female rat oral exposure to triclosan and includes hormone, estrous cyclicity, thyroid histology and liver gene... -
Federal
Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase
U.S. Environmental Protection Agency —
Supplementary materials for "Olker JH, Korte JJ, Haselman JT, Hornung MW, Degitz SJ. Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine... -
Federal
FRTL-5 RAIU of 5-AT
U.S. Environmental Protection Agency —
Iodide uptake following a two-hour incubation with concentrations of 5-ATcompared to control iodide uptake in FRTL thyroid follicular cells. This dataset is... -
Federal
Data supporting amphibian thyroid model parameterization
U.S. Environmental Protection Agency —
This dataset was generated to support parameterization of a larval amphibian thyroid axis computational model. Specifically, plasma iodine levels were determined not... -
Federal
Data tables, and data used in figures presented in the manuscript "High-Throughput Screening and Chemotype-Enrichment Analysis of ToxCast Phase II Chemicals Evaluated for Human Sodium-Iodide Symporter (NIS) Inhibition"
U.S. Environmental Protection Agency —
All tables, plus the data for generating figures presented in the manuscript "High-Throughput Screening and Chemotype-Enrichment Analysis of ToxCast Phase II... -
Federal
Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening
U.S. Environmental Protection Agency —
The objective of this study was to develop a medium-throughput organotypic screening assay comprised of reconstructed human thyroid microtissues to quantitatively... -
Federal
Data Table for Figures
U.S. Environmental Protection Agency —
This excel file contains 7 tabs, each tabs contains the data for one specific figure in the paper. Description of the data and column names is also provided in each... -
Federal
Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
U.S. Environmental Protection Agency —
The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database... -
Federal
Xenpous leavis deiodinase type 3 enzyme activity characterization and chemical screening data
U.S. Environmental Protection Agency —
Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast... -
Federal
Data for "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain"
U.S. Environmental Protection Agency —
Raw data accompanying "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain". This dataset is...