Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
The data set consists of the following:
1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network.
2) A literature database containing all literature that was cited in the main document. The database also contains additional references that were not explicitly cited in the associated manuscript.
3) R code used for the analyses and visualizations
4) Detailed results from the SeqAPASS tool.
This dataset is associated with the following publication:
Haigis, A., L. Vergauwen, C. LaLone, D. Villeneuve, J. O'Brien, and D. Knapen. Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 195(1): 1-27, (2023).
Resources
4 resources available
-
https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16
FILE -
R-files.zip
APPLICATION/ZIP -
SeqAPASS-details.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
literature-database.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Daniel Villeneuve", "hasEmail": "mailto:villeneuve.dan@epa.gov" } |
| description | The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database containing all literature that was cited in the main document. The database also contains additional references that were not explicitly cited in the associated manuscript. 3) R code used for the analyses and visualizations 4) Detailed results from the SeqAPASS tool. This dataset is associated with the following publication: Haigis, A., L. Vergauwen, C. LaLone, D. Villeneuve, J. O'Brien, and D. Knapen. Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 195(1): 1-27, (2023). |
| distribution |
[ { "title": "https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16", "accessURL": "https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16" }, { "title": "R-files.zip", "mediaType": "application/zip", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/R-files.zip" }, { "title": "SeqAPASS-details.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/SeqAPASS-details.xlsx" }, { "title": "literature-database.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529155/literature-database.xlsx" } ] |
| identifier | https://doi.org/10.23719/1529155 |
| keyword |
[ "Adverse Outcome Pathways (AOPs)", "cross-species extrapolation", "endocrine disruption", "thyroid" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2023-06-23 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1093/toxsci/kfad063" ] |
| rights |
null
|
| title | Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption |
