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Supplemental materials for "The thyroid hormone system disrupting potential of resorcinol in fish". This dataset is associated with the following publication: Van Dingenen, I., E. Andersen, S....
Search relevance: 1.00 | Views last month: 32 | Catalog Last Checked: April 21, 2026 at 08:08 PM -
These data represent surface water and bed sediment samples analyzed for a variety of organic compounds. The samples were collected in streams and rivers in the Chesapeake Bay watershed from...
Search relevance: 1.00 | Views last month: 8 | Catalog Last Checked: May 05, 2026 at 10:12 PM -
This data release presents chemical and biological results from investigations of water quality, fish endocrine disruption, and emergent insects in the Shenandoah River Watershed (Virginia and...
Search relevance: 1.00 | Views last month: 5 | Catalog Last Checked: May 05, 2026 at 08:38 PM -
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational models on high-throughput...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: April 21, 2026 at 07:56 PM -
Decades of poor reproductive success and young-of-the-year recruitment, in addition to adult mortality, has led to a decline in the smallmouth bass (SMB) population in subwatersheds of the Potomac...
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The dataset includes survival of control, control injected, and CRISPR/Cas9 injected embryos as well as percent efficiency of insertion/deletion mutation formation for the three different CRISPR...
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This excel file contains the resultant data from a study on iodotyrosine deiodinase in the model amphibian species, Xenopus laevis. These data include: tadpole growth and development, thyroid...
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The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR) antagonist, flutamide....
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: April 21, 2026 at 07:57 PM -
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist activity. Active compounds were...
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This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations would result in elevated plasma...
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Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
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Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone metabolism manuscript. File...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: April 21, 2026 at 07:58 PM -
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in ovary, prostaglandin...
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Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro screening assays through...
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As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity ratios (EARs) as a...
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This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: April 21, 2026 at 08:00 PM -
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: April 21, 2026 at 07:59 PM -
HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were downloaded and converted from...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: April 21, 2026 at 08:01 PM -
Largemouth base histological development and transcriptomic changes in gonad tissue after early life stage exposure to Atrazine (1-Chloro-3-ethylamino-5-isopropylamino-2,4,6-triazine) or the model...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: May 05, 2026 at 07:25 PM -
The datafile contains data associated with analytical chemistry, fish gene expression, in vitro bioassays, chemical prioritization, and Attagene data for surface water monitoring and caged fish...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: April 21, 2026 at 08:02 PM
