57 datasets found
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Federal
Aggregated Computational Toxicology Online Resource
U.S. Environmental Protection Agency —
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from... -
Federal
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project
U.S. Environmental Protection Agency —
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational... -
Federal
Consumer Product Category Database
U.S. Environmental Protection Agency —
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use... -
Federal
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
U.S. Environmental Protection Agency —
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content... -
Federal
ToxCast Phase I
U.S. Environmental Protection Agency —
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental... -
Federal
Distributed Structure Searchable Toxicity
U.S. Environmental Protection Agency —
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It... -
Federal
Structural alerts for protein binding
U.S. Environmental Protection Agency —
The JRC dataset (doi: 10.1016/j.tiv.2016.07.014) includes reported outcomes in chemico, in vitro and in vivo tests for skin sensitisation. The Tox21 dataset was... -
Federal
Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing
U.S. Environmental Protection Agency —
Data and code for "Grace Patlewicz, Ann M. Richard, Antony J. Williams, Richard S. Judson, Russell S. Thomas, Towards reproducible structure-based chemical categories... -
Federal
The ToxCast pipeline: updates to curve-fitting approaches and database structure
U.S. Environmental Protection Agency —
Supplemental files to accompany the manuscript: Feshuk et al., "The ToxCast Pipeline: Updates to Curve-fitting Approaches and Database Structure", DOI... -
Federal
Respirometric Screening and Characterization of Mitochondrial Toxicants Within the ToxCast Phase I and II Chemical Libraries
U.S. Environmental Protection Agency —
These are the raw data files for TOXSCI manuscript 19-0578 entitled, “Respirometric Screening and Characterization of Mitochondrial Toxicants Within the ToxCast Phase... -
Federal
MMartin_DFiler_tcpl: the ToxCast pipeline for high-throughput screening data
U.S. Environmental Protection Agency —
The tcpl package provides a set of tools for processing and modeling high-throughput and high-content chemical screening data. This dataset is associated with the... -
Federal
Exposure Forecaster
U.S. Environmental Protection Agency —
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure... -
Federal
Judson_RefChem_InVitro_Assays
U.S. Environmental Protection Agency —
This supplemental material describes two sets of methods; first, it briefly describes the process used to create the EPA’s LitDB database, and second, it describes... -
Federal
Data from Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries
U.S. Environmental Protection Agency —
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge... -
Federal
Tox21BodyMap: A webtool to map chemical effects on the human body
U.S. Environmental Protection Agency —
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body,... -
Federal
Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity
U.S. Environmental Protection Agency —
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis,... -
Federal
HTTK R Package v1.7 - Evaluation and Calibration of High-Throughput Predictions of Chemical Distribution to Tissues
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
HTTK R Package v1.0
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
High-throughput Toxicogenomic Screening of Chemicals in the Environment Using Metabolically Competent, Human-derived Hepatic Cell Cultures
U.S. Environmental Protection Agency —
Gene expression data from the Fluidigm qRT-PCR arrays was analyzed in R (v3.6.1; R Foundation for Statistical Computing, 2019). Prior to processing through the tcpl... -
Federal
Evaluation of a Multiplexed, Multispecies Nuclear Receptor Assay for Chemical Hazard Assessment
U.S. Environmental Protection Agency —
Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement...
57 datasets found