57 datasets found
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Federal
Consumer Product Category Database
U.S. Environmental Protection Agency —
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use... -
Federal
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
U.S. Environmental Protection Agency —
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content... -
Federal
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project
U.S. Environmental Protection Agency —
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational... -
Federal
Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature
U.S. Environmental Protection Agency —
A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database... -
Federal
Exposure Forecaster
U.S. Environmental Protection Agency —
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure... -
Federal
Interactive Chemical Safety for Sustainablity Toxicity Forecaster Dashboard
U.S. Environmental Protection Agency —
EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800... -
Federal
ToxCast Phase I
U.S. Environmental Protection Agency —
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental... -
Federal
Aggregated Computational Toxicology Online Resource
U.S. Environmental Protection Agency —
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from... -
Federal
Read_Across_Prediction_of_Estrogenicity_for_Hindered_Phenols_2017_Data
U.S. Environmental Protection Agency —
Read-across is an important data gap filling technique used within category and analog approaches for regulatory hazard identification and risk assessment. Although... -
Federal
High-throughput Toxicogenomic Screening of Chemicals in the Environment Using Metabolically Competent, Human-derived Hepatic Cell Cultures
U.S. Environmental Protection Agency —
Gene expression data from the Fluidigm qRT-PCR arrays was analyzed in R (v3.6.1; R Foundation for Statistical Computing, 2019). Prior to processing through the tcpl... -
Federal
Tox21BodyMap: A webtool to map chemical effects on the human body
U.S. Environmental Protection Agency —
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body,... -
Federal
Food, Beverage, and Feedstock Processing Facility Wastewater: a Unique and Underappreciated Source of Contaminants to U.S. Streams
U.S. Environmental Protection Agency —
PCA contribution of variables; stacked barplot of PFAS compounds by facility; detected concentrations and corresponding exposure–activity ratios; toxicity quotients... -
Federal
RJudson_Mansouri_CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity
U.S. Environmental Protection Agency —
Data and supplemental files from COMPARA (A large-scale modeling project). COMPARA combined multiple models developed in collaboration with modelers and computational... -
Federal
Dataset for 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping'
U.S. Environmental Protection Agency —
Dataset for Harrill, J.A. et al., 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping' published in... -
Federal
ATP BINDING CASSETTE SUB-FAMILY MEMBER 2 (ABCG2) AND XENOBIOTIC EXPOSURE DURING EARLY MOUSE EMBRYONIC STEM CELL DIFFERENTIATION
U.S. Environmental Protection Agency —
ATP binding cassette sub-family member 2 (ABCG2) is a well-defined efflux transporter found in various tissues. The role of ABCG2 during early embryonic development,... -
Federal
Distributed Structure Searchable Toxicity
U.S. Environmental Protection Agency —
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It... -
Federal
Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity
U.S. Environmental Protection Agency —
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis,... -
Federal
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
U.S. Environmental Protection Agency —
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here,... -
Federal
HTTK: R Package for High-Throughput Toxicokinetics
U.S. Environmental Protection Agency —
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have... -
Federal
HTTK R Package v1.4 - JSS Article on HTTK: R Package for High-Throughput Toxicokinetics
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from...
57 datasets found