Data Catalog

• Federal

  Extrapolating In Vitro and Ex Vivo Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat

  U.S. Environmental Protection Agency —

  This data set is a dose response analysis of two thyroid hormone synthesis disruptors in adult male rats. Data included serum and thyroid gland concentrations of the...

  • XLS
• Federal

  Deiodinase Types 1, 2, and 3: Screening of ToxCast Phase 1_v2, Phase 2, and e1k Chemical Libraries

  U.S. Environmental Protection Agency —

  These excel spreadsheets contains the resultant data from inhibition assays with human Iodothyronine Deiodinase Types 1, 2, and 3 screened against the ToxCast Phase...

  • XLS
• Federal

  Human Iodotyrosine Deiodinase Inhibition Assay: Screening of ToxCast Phase 1_v2, Phase 2, and e1k Chemical Libraries

  U.S. Environmental Protection Agency —

  The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the...

  • XLS
• Federal

  Quantitative Adverse Outcome Pathway for Neurodevelopmental Effects of Thyroid Peroxidase-Induced Thyroid Hormone Synthesis Inhibition

  U.S. Environmental Protection Agency —

  Adequate levels of thyroid hormones (TH) are needed for proper brain development, deficiencies may lead to adverse neurological outcomes in humans and animal models....

  • XLS
• Federal

  Deiodinase 1 Screening of ToxCast Phase 1 Chemical Library

  U.S. Environmental Protection Agency —

  This excel spreadsheet contains the resultant data for over from inhibition assays with human Deiodinase 1 screened against the ToxCast Phase 1 chemical library and a...

  • XLS
• Federal

  Fox River kindling Bandara et al Summary Data

  U.S. Environmental Protection Agency —

  This study looked at functional endpoints in adult offspring of rats exposed in utero and postnatally to an environmentally relevant mixture of PCBs, Fox River blend....

  • XLS
• Federal

  Ramjoh PFHxS Data

  U.S. Environmental Protection Agency —

  File contains data on body, liver, thyroid weights from dams and exposed offspring, serum thyroid hormones, gland and cortical gene expression, results of cognitive...

  • XLS

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