A high throughput screening assay for human Thyroperoxidase inhibitors
Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology in Vitro, Vol 101, 105946, Dec 2024; DOI https://doi.org/10.1016/j.tiv.2024.105946. Supplementary Data File 1: Examples of two solution plates and the resulting assay plate layouts for Single concentration phase. Supplementary Data File 2: The tcpl analyses of all multiple concentration phase data including plots of fitted models, estimates of log AC50 (ga), and hit call. Supplementary Data File 3: Supplementary Tables 1-5. For further data, please contact corresponding author Hongyan Dong at email Hongyan.Dong@hc-sc.gc.ca.
This dataset is associated with the following publication:
Dong, H., K. Friedman, A. Filiatreault, E. Thomson, and M. Wade. A high throughput screening assay for human Thyroperoxidase inhibitors. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 101: 105946, (2024).
Resources
3 resources available
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1-s2.0-S0887233324001760-Supplement1.docx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.WORDPROCESSINGML.DOCUMENT -
1-s2.0-S0887233324001760-Supplement2.pdf
APPLICATION/PDF -
1-s2.0-S0887233324001760-Supplement3.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Katie Friedman",
"hasEmail": "mailto:paul-friedman.katie@epa.gov"
}
|
| description | Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology in Vitro, Vol 101, 105946, Dec 2024; DOI https://doi.org/10.1016/j.tiv.2024.105946. Supplementary Data File 1: Examples of two solution plates and the resulting assay plate layouts for Single concentration phase. Supplementary Data File 2: The tcpl analyses of all multiple concentration phase data including plots of fitted models, estimates of log AC50 (ga), and hit call. Supplementary Data File 3: Supplementary Tables 1-5. For further data, please contact corresponding author Hongyan Dong at email Hongyan.Dong@hc-sc.gc.ca. This dataset is associated with the following publication: Dong, H., K. Friedman, A. Filiatreault, E. Thomson, and M. Wade. A high throughput screening assay for human Thyroperoxidase inhibitors. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 101: 105946, (2024). |
| distribution |
[
{
"title": "1-s2.0-S0887233324001760-Supplement1.docx",
"mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement1.docx"
},
{
"title": "1-s2.0-S0887233324001760-Supplement2.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement2.pdf"
},
{
"title": "1-s2.0-S0887233324001760-Supplement3.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement3.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1532100 |
| keyword |
[
"Screening assay",
"Thyroid peroxidase",
"endocrine disruption",
"thyroid hormone"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2024-07-16 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1016/j.tiv.2024.105946"
]
|
| rights |
null
|
| title | A high throughput screening assay for human Thyroperoxidase inhibitors |
