6 datasets found
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Federal
The Application of a Highly Purified Rat Leydig Cell Assay as a Complement to the H295R Steroidogenesis Assay for the Evaluation of Toxicant Induced Alterations in Testosterone Production
U.S. Environmental Protection Agency —
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not... -
Federal
Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening
U.S. Environmental Protection Agency —
Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et... -
Federal
High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells
U.S. Environmental Protection Agency —
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-... -
Federal
Defining the Taxonomic Domain of Applicability for Mammalian-Based High-Throughput Screening Assays
U.S. Environmental Protection Agency —
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins... -
Federal
The Application of a Highly Purified Rat Leydig Cell Assay as a Complement to the H295R Steroidogenesis Assay to Evaluate Toxicant Induced Alterations in Testosterone Production
U.S. Environmental Protection Agency —
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not... -
Federal
Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis
U.S. Environmental Protection Agency —
Dataset from Foster, M.J., et al., Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis, Computational Toxicology, Vol 24, No....
6 datasets found