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The Application of a Highly Purified Rat Leydig Cell Assay as a Complement to the H295R Steroidogenesis Assay to Evaluate Toxicant Induced Alterations in Testosterone Production

Metadata Updated: November 12, 2020

The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput screening format of the H295R steroidogenesis assay. This dataset is associated with ORD-022468 entered in STICS.

This dataset is associated with the following publication: Botteri Principato, N., J. Suarez, S. Laws, and G. Klinefelter. The Use of Purified Rat Leydig Cells Complements the H295R Screen to Detect Chemical Induced Alterations in Testosterone Production. BIOLOGY OF REPRODUCTION. Society for the Study of Reproduction, 98(2): 239-249, (2018).

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Public: This dataset is intended for public access and use. License: See this page for license information.

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Metadata Created Date November 12, 2020
Metadata Updated Date November 12, 2020

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date November 12, 2020
Metadata Updated Date November 12, 2020
Publisher U.S. EPA Office of Research and Development (ORD)
Data Last Modified 2017-06-16
Public Access Level public
Bureau Code 020:00
Schema Version
Harvest Object Id f3803bb7-07f1-4f0f-8b58-9fc544bf1ba6
Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
Harvest Source Title EPA ScienceHub
Program Code 020:000
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents
Source Datajson Identifier True
Source Hash b893d64cb519d68f4882253e0b4e3e8d88a153c2
Source Schema Version 1.1

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