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Federal
Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling
U.S. Department of Health & Human Services —
Background: Ventilator-associated bacterial pneumonia (VAP) is a important intensive care unit (ICU)-acquired infection in mechanically ventilated patients. Early and... -
Federal
Oral contraceptive use before first birth and risk of breast cancer: a case control study
U.S. Department of Health & Human Services —
Background The aim of this study was first, to investigate whether women starting oral contraceptive (OC) use at a young age and before first birth have an increased... -
Federal
Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? A meta analysis of randomized clinical trials
U.S. Department of Health & Human Services —
Background Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms.... -
Federal
Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome
U.S. Department of Health & Human Services —
Background In humans, there are four alkaline phosphatases, and each form exibits a characteristic pattern of tissue distribution. The availability of an easy method... -
Federal
Expense and benefit of neoadjuvant treatment in squamous cell carcinoma of the esophagus
U.S. Department of Health & Human Services —
Background The effectiveness of neoadjuvant treatment (NT) prior to resection of squamous cell carcinoma of the esophagus (SCCE) in terms of prolonged survival has... -
Federal
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer
U.S. Department of Health & Human Services —
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
"Bronchial Artery Delivery of Viral Vectors for Gene delivery in Cystic Fibrosis; Superior to Airway Delivery?"
U.S. Department of Health & Human Services —
Background Attempts at gene therapy for the pulmonary manifestations of Cystic Fibrosis have relied mainly on airway delivery. However the efficiency of gene transfer... -
Federal
Autoantibody profiling for the study and treatment of autoimmune disease
U.S. Department of Health & Human Services —
Proteomics technologies enable profiling of autoantibody responses using biological fluids derived from patients with autoimmune disease. They provide a powerful tool... -
Federal
Treatment of established postoperative nausea and vomiting: a quantitative systematic review
U.S. Department of Health & Human Services —
Background The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. Methods Systematic search... -
Federal
Specificity of T cells in synovial fluid: high frequencies of CD8
U.S. Department of Health & Human Services —
CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or... -
Federal
Blood substitutes Artificial oxygen carriers: perfluorocarbon emulsions
U.S. Department of Health & Human Services —
Perfluorocarbon emulsions are being clinically evaluated as artificial oxygen carriers to reduce allogeneic blood transfusions or to improve tissue oxygenation.... -
Federal
Oral sildenafil (Viagra™) in male erectile dysfunction: use, efficacy and safety profile in an unselected cohort presenting to a British district general hospital.
U.S. Department of Health & Human Services —
Introduction Sildenafil (Viagra®) is one of the drugs used in the first line therapy of male erectile dysfunction (MED). We have recorded outcomes, adverse events and... -
Federal
Human members of the eukaryotic protein kinase family
U.S. Department of Health & Human Services —
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling... -
Federal
Bone mineral density and the subsequent risk of cancer in the NHANES I follow-up cohort
U.S. Department of Health & Human Services —
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of... -
Federal
Safety of a new extensively hydrolysed formula in children with cow's milk protein allergy: a double blind crossover study
U.S. Department of Health & Human Services —
Background Formulae for infants with cow's milk protein allergy (CMA) should be based on extensively hydrolysed protein. 'Extensively' however is not strictly... -
Federal
Prehospital point of care testing of blood gases and electrolytes — an evaluation of IRMA
U.S. Department of Health & Human Services —
Background: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. Results: A... -
Federal
Early immune development, atopy and asthma: insights from ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
There is rising evidence that the initiation of atopy and asthma may occur in early life or even during fetal life. At the American Thoracic Society meeting 2001 in... -
Federal
The evaluation of yeast derivatives as adjuvants for the immune response to the Bm86 antigen in cattle
U.S. Department of Health & Human Services —
Background The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this... -
Federal
A clustering method for repeat analysis in DNA sequences
U.S. Department of Health & Human Services —
Background A computational system for analysis of the repetitive structure of genomic sequences is described. The method uses suffix trees to organize and search the...