51 datasets found
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Federal
Transcription profiling of atm mutant adm mutant and wild type whole plants and roots of Arabidopsis after gamma ray irradiation in a time series
National Aeronautics and Space Administration —
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Efficient Identification of Multiple Pathways: RNA-Seq Analysis of Livers from 56Fe Ion Irradiated Mice
National Aeronautics and Space Administration —
Background: mRNA interactions with each other and other signaling molecules define different biological pathways and functions. Researchers have been investigating... -
Federal
Gene expression profiles of irradiated lung tissue in three mouse strains
National Aeronautics and Space Administration —
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in... -
Federal
Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation
National Aeronautics and Space Administration —
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer
National Aeronautics and Space Administration —
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in... -
Federal
Gene expression profiles of irradiated lung tissue in three mouse strains
National Aeronautics and Space Administration —
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Transcriptomic analysis of spleens from mice subjected to chronic low-dose radiation hindlimb unloading or a combination of both
National Aeronautics and Space Administration —
The purpose of this study was to evaluate transcriptional changes in mouse spleens using a ground-based model for spaceflight. This model includes prolonged unloading... -
Federal
Radiation-induced bystander effects and gene expression in cells deficient for RAD9
National Aeronautics and Space Administration —
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Liver tissue
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Soleus muscle
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Gene expression profiling of PBL in response to ionising radiation and modeled microgravity
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Plasma
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Gene expression in blood of mice with internal exposure to Cs-137
National Aeronautics and Space Administration —
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an... -
Federal
Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure
National Aeronautics and Space Administration —
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling.... -
Federal
Global DNA methylation profiling of radiation-induced rat mammary carcinomas
National Aeronautics and Space Administration —
To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat...
51 datasets found