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    • Transcription profiling of atm mutant adm mutant and wild type whole plants and roots of Arabidopsis after gamma ray irradiation in a time series

    Metadata Updated: December 7, 2023

    Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and atr (4d) mutants have been analyzed after a 1h irradiation. Ataxia Telangiectasia Mutated (ATM) encodes a large protein with a phosphatidylinositol 3-kinase (PI3K)-like domain at the C terminus (reviewed by Rotman and Shiloh 1998). PI3K-related proteins make up a large family of Ser-Thr protein kinases numerous members of which are involved in the regulation of cell cycle progression responses to DNA damage and the maintenance of genomic stability (Hoekstra 1997). AtATM plays an essential role in meiosis and in the somatic response to DNA damage in plants similar to the function of ATM in mammals and other eukaryotes. Ataxia telangiectasia-mutated and Rad3-related (ATR) plays a central role in cell-cycle regulation transmitting DNA damage signals to downstream effectors of cell-cycle progression.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: us-pd

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    Dates

    Metadata Created Date February 1, 2023
    Metadata Updated Date December 7, 2023
    Data Update Frequency irregular

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date February 1, 2023
    Metadata Updated Date December 7, 2023
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-329_yw48-ec8a
    Data First Published 2021-05-21
    Data Last Modified 2023-01-26
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Metadata Catalog ID https://data.nasa.gov/data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 447a1c66-8653-4659-a696-04e6175b3e61
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://data.nasa.gov/d/yw48-ec8a
    License http://www.usa.gov/publicdomain/label/1.0/
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 1c6194ad3b77d1b3c35ea572c34e959129870ff35b2cf95bcbd2e6842eb0ff95
    Source Schema Version 1.1

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