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Federal
Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural... -
Federal
Spaceflight effects on the mouse retina: Histological, gene expression and epigenetic changes after flight on STS-135
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Transcriptomic response of Drosophila melanogaster pupae developed in hypergravity
National Aeronautics and Space Administration —
Physical forces greatly influence the growth and function of an organism. Altered gravity can perturb normal development and induce corresponding changes in gene... -
Federal
Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA, DNA, and protein were purified... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface, Kirovograd region soil, Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight
National Aeronautics and Space Administration —
The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe, non-invasive, daily... -
Federal
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight
National Aeronautics and Space Administration —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
Federal
Draft Genome Sequences of Members of the family Methylobacteriaceae Associated with the International Space Station
National Aeronautics and Space Administration —
Draft Genome Sequences of isolates belonging to family Methylobacteriaceae Isolated from the International Space Station -
Federal
ISS Bacillus Genomes
National Aeronautics and Space Administration —
SRA of spore forming Bacillus strains isolated from various areas of the ISS during Microbial tracking investigation -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment, and then we ask whether undifferentiated cells, cells... -
Federal
Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress related damage in the murine retina (RR-9)
National Aeronautics and Space Administration —
Extended spaceflight has been shown to adversely affect astronaut visual acuity. The purpose of this study was to determine whether spaceflight alters gene expression... -
Federal
Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids - Drosophila data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Spaceflight adaptation requires organ specific alterations in the proteomes of Arabidopsis
National Aeronautics and Space Administration —
Life in spaceflight demonstrates remarkable adaptive processes within the specialized environments of space vehicles which are subject to the myriad of attending and... -
Federal
Rodent Research-3-CASIS: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays
National Aeronautics and Space Administration —
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays, or 10 cGy or 30 cGy densely ionizing... -
Federal
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth
National Aeronautics and Space Administration —
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness... -
Federal
Genome sequencing of Staphylococcus, Burkholderia, and Ralstonia bacterial isolates isolated from the ISS
National Aeronautics and Space Administration —
This repository holds genome assemblies for Staphylococcus, Burkholderia, and Ralstonia bacterial isolates isolated from the ISS between the years of 2006-2015.... -
Federal
Transcriptional profiling of adrenal glands from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
Draft Genome Sequences of novel Agrobacterium genomospecies 3 Associated from the International Space Station
National Aeronautics and Space Administration —
The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being...