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    • Rodent Research-3-CASIS: Mouse liver transcriptomic, proteomic, epigenomic and histology data

    Metadata Updated: August 30, 2025

    The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c, 12-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the Rodent Habitat for 39-42 days. Twenty mice of similar age, sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight, ground controls and basal groups had blood collected, then were euthanized, had one hind limb removed, and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

    Downloads & Resources

    Dates

    Metadata Created Date April 11, 2025
    Metadata Updated Date August 30, 2025

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date April 11, 2025
    Metadata Updated Date August 30, 2025
    Publisher Open Science Data Repository
    Maintainer
    Identifier 10.26030/9k6w-4c28
    Data Last Modified 2025-08-21
    Category Biological and Physical Sciences
    Public Access Level public
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 5248bcec-5c40-433c-aacf-bf6044dd8e77
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://osdr.nasa.gov/bio/repo/data/missions/SpaceX-8
    Program Code 026:000
    Source Datajson Identifier True
    Source Hash 528951720208c9804fccc364e9b3cf5972fed69890c5632ab52e308f1aa03a0a
    Source Schema Version 1.1

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