-
Federal
Agonizing Hedgehog
U.S. Department of Health & Human Services —
It is a rare treat when a drug discovery program teaches us something about the biology of the process that it attempts to modulate. The paper by Maria Frank-... -
Federal
Biventricular pacing in heart failure: update on results from clinical trials
U.S. Department of Health & Human Services —
Biventricular pacing or resynchronisation therapy is a non-pharmacological therapy for patients with chronic heart failure. Since being originally described in 1994,... -
Federal
Human members of the eukaryotic protein kinase family
U.S. Department of Health & Human Services —
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling... -
Federal
Sunlight and skin cancer
U.S. Department of Health & Human Services —
Sunlight and skin cancer -
Federal
Blood substitutes Artificial oxygen carriers: perfluorocarbon emulsions
U.S. Department of Health & Human Services —
Perfluorocarbon emulsions are being clinically evaluated as artificial oxygen carriers to reduce allogeneic blood transfusions or to improve tissue oxygenation.... -
Federal
Value Set Authority Center
U.S. Department of Health & Human Services —
The VSAC is a repository and authoring tool for public value sets created by external programs. Value sets are lists of codes and corresponding terms, from NLM-hosted... -
Federal
Blood substitutes: Haemoglobin therapeutics in clinical practice
U.S. Department of Health & Human Services —
Early approaches to the development of oxygen carriers involved the use of stroma-free hemoglobin solutions. These solutions did not require blood typing or... -
Federal
Asymmetric directional mutation pressures in bacteria
U.S. Department of Health & Human Services —
When there are no strand-specific biases in mutation and selection rates between the two strands of DNA, the average nucleotide composition is theoretically expected... -
Federal
Reporting of conflicts of interest in guidelines of preventive and therapeutic interventions
U.S. Department of Health & Human Services —
Background Guidelines published in major medical journals are very influential in determining clinical practice. It would be essential to evaluate whether conflicts... -
Federal
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer
U.S. Department of Health & Human Services —
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in... -
Federal
In what extent anemia coexists with cognitive impairment in elderly: a cross-sectional study in Greece
U.S. Department of Health & Human Services —
Background A project aimed at studying the frequency of dementia and depression in the catchment area of the Health Centre of Chrissoupolis (HCCh), Northern Greece,... -
Federal
Mechanical ventilation in rural ICUs
U.S. Department of Health & Human Services —
Background: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care... -
Federal
The role of X-chromosome inactivation in female predisposition to autoimmunity
U.S. Department of Health & Human Services —
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
Genetic polymorphisms in lung disease: bandwagon or breakthrough?
U.S. Department of Health & Human Services —
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to... -
Federal
Plasma colloid osmotic pressure in healthy infants
U.S. Department of Health & Human Services —
Background The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants... -
Federal
VirOligo: a database of virus-specific oligonucleotides
U.S. Department of Health & Human Services —
VirOligo is a database of virus-specific oligonucleotides. The VirOligo database consists of two tables, Common data and Oligo data. The Oligo data table contains PCR... -
Federal
Approaches to enhancing the retroviral transduction of human synoviocytes
U.S. Department of Health & Human Services —
This report concerns a clinical trial for rheumatoid arthritis (RA), approved by the US National Institutes of Health and the Food and Drug Administration. An... -
Federal
Pacing in congestive heart failure
U.S. Department of Health & Human Services —
Despite the major advances in medical drug therapy, heart failure remains a syndrome associated with high mortality and morbidity. Biventricular or left ventricular... -
Federal
Specificity of T cells in synovial fluid: high frequencies of CD8
U.S. Department of Health & Human Services —
CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or...