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Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals
This is a new, open, and transparent database of toxicokinetic data supporting EPA decision making. The database has already become the basis of research efforts within EPA to... -
Consumer Product Category Database
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use information is... -
Honda_Wambaugh_Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions
All relevant data are within the manuscript, its Supporting Information files, and the httk R software package v1.9.2. This dataset is associated with the following publication:... -
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the... -
Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization
The supplemental information for this paper includes chemical-specific analytical methods, raw instrument data for chemical concentration analysis, processed data for... -
Quantitative Structure-Use Relationship (QSUR) Model Descriptors
This data set contains ToxPrint finger prints for all chemicals in FUse that had QSAR-ready SMILES strings as well as select physicochemical properties from the Estimation... -
Functional Use Database (FUse)
There are five different files for this dataset: 1. A dataset listing the reported functional uses of chemicals (FUse) 2. All 729 ToxPrint descriptors obtained from ChemoTyper... -
Development and Evaluation of a High Throughput Inhalation Model for Organic Chemicals
This investigation was broken down into three interrelated steps: data collection, model building, and model evaluation. R software (v. 3.5.1) with the httk package (v. 1.9) was... -
HTTK R Package v1.5 - Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high... -
Abstract Sifter: a comprehensive front-end system to PubMed
The Abstract Sifter is a Microsoft Excel based application that enhances existing search capabilities of PubMed. The Abstract Sifter assists researchers to search effectively,... -
(REPRODUCTIVE TOXICOLOGY) EMBRYONIC VASCULAR DISRUPTION ADVERSE OUTCOMES: LINKING HIGH THROUGHPUT SIGNALING SIGNATURES WITH FUNCTIONAL CONSEQUENCES
This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional assays: the... -
Chemical product and function dataset
Merged product weight fraction and chemical function data. This dataset is associated with the following publication: Isaacs , K., M. Goldsmith, P. Egeghy , K. Phillips, R.... -
CES_EHP_Figure_2
The increasing number of chemicals for which SHEDS probabilistic exposure assessment has been performed over the years. This dataset is associated with the following... -
Development of a Flame Retardant and an Organohalogen Flame Retardant Chemical Inventory
This dataset is the result of a joint EPA-CPSC effort to catalogue flame retardant (and more specifically organohalogen flame retardant chemicals). Full details of how the data... -
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro... -
Suspect Screening Analysis of Chemicals in Consumer Products
A suspect screening analysis method is presented to rapidly characterize chemicals in 100 consumer products -- whether they be formulations (shampoos, paints), articles... -
Estimation of the Emission Characteristics of SVOCs from Household Articles Using Group-Contribution Methods
The attached dataset, including data dictionary, provides all the EPA-generated data for the publication Estimation of the Emission Characteristics of SVOCs from Household... -
Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells
Raw data and figures for Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-... -
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion
Paper studying synthetic hydrogels as an alternative to matrigel. This dataset is not publicly accessible because: Research data consisted of secondary data only. It can be... -
Datasets associated with "Mining of Consumer Product and Purchasing Data to Identify Potential Chemical Co-exposures"
Background: Chemicals in consumer products are a major contributor to human chemical co-exposures. Consumers purchase and use a wide variety of products containing potentially...
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