Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization
Resources
7 resources available
-
https://cran.r-project.org/package=httk
FILE -
https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data
FILE -
SupTable1-AnalyticalMethods.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
SupTable2-RawPPBData.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
SupTable3-RawCLintData.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
SupTable4-ProcessedData.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
SupplementalFigures4.pdf
APPLICATION/PDF
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "John Wambaugh",
"hasEmail": "mailto:wambaugh.john@epa.gov"
}
|
| description | The supplemental information for this paper includes chemical-specific analytical methods, raw instrument data for chemical concentration analysis, processed data for experiments on intrinsic hepatic clearance (CLint -- metabolism) and chemical fraction unbound in the presence of human plasma protein (fup). Figures showing the curve fits for determining CLint are provided. Finally, all data were released publicly as HTTK R Package v1.10.1. This dataset is associated with the following publication: Wambaugh, J., B. Wetmore, C. Ring, C. Nicolas, R. Pearce, G. Honda, R. Dinallo, D. Angus, J. Gilbert, T. Sierra, A. Badrinarayanan, B. Snodgrass, A. Brockman, C. Strock, R. Setzer, and R. Thomas. Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 172(2): 235-251, (2019). |
| distribution |
[
{
"title": "https://cran.r-project.org/package=httk",
"accessURL": "https://cran.r-project.org/package=httk"
},
{
"title": "https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data",
"accessURL": "https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data"
},
{
"title": "SupTable1-AnalyticalMethods.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable1-AnalyticalMethods.xlsx"
},
{
"title": "SupTable2-RawPPBData.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable2-RawPPBData.xlsx"
},
{
"title": "SupTable3-RawCLintData.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable3-RawCLintData.xlsx"
},
{
"title": "SupTable4-ProcessedData.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable4-ProcessedData.xlsx"
},
{
"title": "SupplementalFigures4.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupplementalFigures4.pdf"
}
]
|
| identifier | https://doi.org/10.23719/1504435 |
| keyword |
[
"ExpoCast",
"exposure"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-05-08 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1093/toxsci/kfz205"
]
|
| rights |
null
|
| title | Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization |
