Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals

Metadata Updated: January 14, 2021

This is a new, open, and transparent database of toxicokinetic data supporting EPA decision making. The database has already become the basis of research efforts within EPA to improve HTTK modeling using generic TK models and has facilitated the creation and validation of models for new exposure routes. Publishing the database supports open, transparent science and this database (the largest public database for this domain) will spur improvement and development of TK models by external experts in the field. Future efforts to improving the accessibility of this database (with a graphical user interface) and encouraging crowdsourcing to expand the size and scope of the database will lead to larger validation sets for our modeling efforts and likely lower uncertainties when estimating TK.

This dataset is associated with the following publication: Sayre, R., J. Wambaugh, and C. Grulke. Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals. Scientific Data. Springer Nature Group, New York, NY, 7: 122, (2020).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

Downloads & Resources

References

https://doi.org/10.1038/s41597-020-0455-1

Dates

Metadata Created Date January 14, 2021
Metadata Updated Date January 14, 2021

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date January 14, 2021
Metadata Updated Date January 14, 2021
Publisher U.S. EPA Office of Research and Development (ORD)
Unique Identifier Unknown
Maintainer
Identifier https://doi.org/10.23719/1504532
Data Last Modified 2019-09-19
Public Access Level public
Bureau Code 020:00
Schema Version https://project-open-data.cio.gov/v1.1/schema
License https://pasteur.epa.gov/license/sciencehub-license.html
Program Code 020:095
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents https://doi.org/10.1038/s41597-020-0455-1
Source Datajson Identifier True
Source Hash c1cd21da693a9fa92869cfe0b9d7a407a62253b0
Source Schema Version 1.1

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