13 datasets found
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Federal
Critical advances in septicemia and septic shock
U.S. Department of Health & Human Services —
Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
Pro/con clinical debate: Are steroids useful in the management of patients with septic shock?
U.S. Department of Health & Human Services —
Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of... -
Federal
Complicated infective endocarditis necessitating ICU admission: clinical course and prognosis
U.S. Department of Health & Human Services —
Aim To study incidence, clinical course and prognostic factors in patients admitted to medical intensive care units (ICUs) because of a complicated course of... -
Federal
Beneficial effect of carboxy-PTIO on hemodynamic and blood gas changes in septic shock dogs
U.S. Department of Health & Human Services —
Background: Nitric oxide (NO) production following bacterial infection may play a physiological role in the host defense mechanism due to its antimicrobial activity.... -
Federal
The International Sepsis Forum's controversies in sepsis: corticosteroids should not be routinely used to treat septic shock
U.S. Department of Health & Human Services —
Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been... -
Federal
The International Sepsis Forum's controversies in sepsis: corticosteroids should be used to treat septic shock
U.S. Department of Health & Human Services —
The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods... -
Federal
Heat stress is associated with decreased lactic acidemia in rat sepsis
U.S. Department of Health & Human Services —
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in... -
Federal
Toll-like receptors: the key to the stable door?
U.S. Department of Health & Human Services —
Severe sepsis continues to lead to critical illness. Few therapeutic options exist other than antibiotic therapy and general supportive care. Large numbers of... -
Federal
Clinical review: Hypertonic saline resuscitation in sepsis
U.S. Department of Health & Human Services —
The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of... -
Federal
Prospectively validated predictions of shock and organ failure in individual septic surgical patients: the Systemic Mediator Associated Response Test
U.S. Department of Health & Human Services —
Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics,... -
Federal
The effects of IgM-enriched immunoglobulin preparations in patients with severe sepsis [ISRCTN28863830]
U.S. Department of Health & Human Services —
Introduction In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ... -
Federal
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
U.S. Department of Health & Human Services —
Introduction Dehydroepiandrosterone (DHEA) and its sulphate (DHEAS) are pleiotropic adrenal hormones with immunostimulating and antiglucocorticoid effects. The...
13 datasets found