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Federal
A study of quality measures for protein threading models
U.S. Department of Health & Human Services —
Background Prediction of protein structures is one of the fundamental challenges in biology today. To fully understand how well different prediction methods perform,... -
Federal
From Protein Sequence to Structure: The Next Frontier in Cross-Species Extrapolation for Chemical Safety Evaluations
U.S. Environmental Protection Agency —
Supplemental data for "LaLone CA, Blatz DJ, Jensen MA, Vliet SMF, Mayasich S, Mattingly KZ, Transue TR, Melendez W, Wilkinson A, Simmons CW, Ng C, Zhang C, Zhang Y.... -
Federal
A comprehensive analysis of 40 blind protein structure predictions
U.S. Department of Health & Human Services —
Background We thoroughly analyse the results of 40 blind predictions for which an experimental answer was made available at the fourth meeting on the critical... -
Federal
Functional evolution of two subtly different (similar) folds
U.S. Department of Health & Human Services —
Background The function of proteins is a direct consequence of their three-dimensional structure. The structural classification of proteins describes the ways of... -
Federal
Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.
U.S. Department of Health & Human Services —
Background Animal and yeast proteins containing long coiled-coil domains are involved in attaching other proteins to the large, solid-state components of the cell.... -
Federal
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra α-helical domain
U.S. Department of Health & Human Services —
The key enzyme in coronavirus polyprotein processing is the viral main proteinase, Mpro, a protein with extremely low sequence similarity to other viral and cellular... -
Federal
The intein of the Thermoplasma A-ATPase A subunit: Structure, evolution and expression in
U.S. Department of Health & Human Services —
Background Inteins are selfish genetic elements that excise themselves from the host protein during post translational processing, and religate the host protein with... -
Federal
Deep Green Unannotated Protein Structures
Department of Energy —
The Deep Green list is based on the identification and curation of conserved unannotated proteins in three green lineage (Viridiplantae) model organisms; Arabidopsis...