7 datasets found
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Federal
An ontology for developmental processes and toxicities of neural tube closure
U.S. Environmental Protection Agency —
The systems map described in this manuscript for neurulation will set the stage for constructing mathematical models and computer simulation of neural tube closure... -
Federal
Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity
U.S. Environmental Protection Agency —
Dataset for Baker, et al., Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity, published in... -
Federal
Computational Model of Secondary Palate Fusion and Disruption ChemResTox Data
U.S. Environmental Protection Agency —
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from... -
Federal
From Protein Sequence to Structure: The Next Frontier in Cross-Species Extrapolation for Chemical Safety Evaluations
U.S. Environmental Protection Agency —
Supplemental data for "LaLone CA, Blatz DJ, Jensen MA, Vliet SMF, Mayasich S, Mattingly KZ, Transue TR, Melendez W, Wilkinson A, Simmons CW, Ng C, Zhang C, Zhang Y.... -
Federal
TZurlinden_pluripotent human (H9) embryonic stem cell
U.S. Environmental Protection Agency —
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel... -
Federal
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics
U.S. Environmental Protection Agency —
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in... -
Federal
Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study Linking Nicotinic Acetylcholine Receptor Activation to Colony Death
U.S. Environmental Protection Agency —
Supporting Information for "Jensen, M.A., Blatz, D.J. and LaLone, C.A. (2023), Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse...
7 datasets found