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    • Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity

    Metadata Updated: November 20, 2023

    Dataset for Baker, et al., Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity, published in journal Altex, https://doi.org/10.14573/altex.2202231

    The two zip files are Excel Macro files, but could not be loaded into SciHub unless they were converted to zip files.

    This tool was built using the EPA's LitDB, a database of MeSH terms from PubMed/Medline records downloaded from NLM. 1. A set of MeSH terms for targets of interest was assembled. 2. The database was searched for occurrences of those terms with antagonist OR agonist subheading in PubMed citations. 3. Non-protein chemicals annotated as major topics in that set of articles was extracted. 4. The chemical MeSH term and the protein target MeSH term were output to Excel in a long format (Detail sheet) and pivot table format (Overview sheet). 5. VBA code was added that allows navigation between the Overview sheet and the Detail sheet.

    This dataset is associated with the following publication: Baker, N., J. Pierro, L. Taylor, and T. Knudsen. Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity. ALTEX. Society ALTEX Edition, Kuesnacht, SWITZERLAND, 40(2): 217-236, (2023).

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

    Downloads & Resources

    References

    https://doi.org/10.14573/altex.2202231

    Dates

    Metadata Created Date November 20, 2023
    Metadata Updated Date November 20, 2023

    Metadata Source

    Harvested from EPA ScienceHub

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date November 20, 2023
    Metadata Updated Date November 20, 2023
    Publisher U.S. EPA Office of Research and Development (ORD)
    Maintainer
    Identifier https://doi.org/10.23719/1529822
    Data Last Modified 2022-06-08
    Public Access Level public
    Bureau Code 020:00
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Harvest Object Id 73986e3a-5bb5-4100-abb7-1a4eb6b92aff
    Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
    Harvest Source Title EPA ScienceHub
    License https://pasteur.epa.gov/license/sciencehub-license.html
    Program Code 020:000
    Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
    Related Documents https://doi.org/10.14573/altex.2202231
    Source Datajson Identifier True
    Source Hash 2a3dc685a2152a2316f747ec4bdf17bd1a4477f9edfee8b806d058ec69af8e7a
    Source Schema Version 1.1

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