59 datasets found
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Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
BASE-A space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid minimal media was sent to the ISS in September 2006 (BASE-A experiment). After 10 days flight R. rubrum cultures returned back to... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
Bacillus subtilis spores PROTECT experiment Space-exposed and Mars-exposed vs. Earth-control
National Aeronautics and Space Administration —
Because of their ubiquity and resistance to spacecraft decontamination bacterial spores are considered likely potential forward contaminants on robotic missions to... -
Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation... -
Federal
Transcription profiling of Drosophila exposed to a levitation magnet for different lengths of time
National Aeronautics and Space Administration —
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5... -
Federal
Woman skeletal muscle transcriptome with bed rest and countermeasures.
National Aeronautics and Space Administration —
Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading... -
Federal
IMR90 bystander experiment 0.5 Gy alpha particle
National Aeronautics and Space Administration —
The existence of a radiation bystander effect in which non-irradiated cells respond to signals from irradiated cells is well established. It raises concerns for the... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment)
National Aeronautics and Space Administration —
Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction... -
Federal
Microarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity
National Aeronautics and Space Administration —
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA... -
Federal
Bacillus subtilis spores PROTECT experiment Space-exposed and Mars-exposed vs. Earth-control
National Aeronautics and Space Administration —
Because of their ubiquity and resistance to spacecraft decontamination bacterial spores are considered likely potential forward contaminants on robotic missions to... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 Gy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 Gy RNA is isolated and labeled using a T7... -
Federal
Salmonella Typhimurium transcription profiles in space flight
National Aeronautics and Space Administration —
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115 and compared to profiles from Salmonella grown under identical... -
Federal
Salmonella Typhimurium transcription profiles in space flight
National Aeronautics and Space Administration —
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115 and compared to profiles from Salmonella grown under identical...
59 datasets found