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Federal
Screening silver nanoparticles for potential neurotoxicity using cortical neurons grown on microelectrode arrays
U.S. Environmental Protection Agency —
the zip files contain outputs from the R-analysis for the nanosilver experiments. This dataset is associated with the following publication: Strickland, J., W. LeFew,... -
Federal
Data set for Vassallo et al
U.S. Environmental Protection Agency —
The dataset contains data from MEA recordings for 6 different compounds that were tested in a concentration-response format. Multiple parameters of neural network... -
Federal
KodavantiP-Acute_HSAB_AOP_Neurotox_Science Hub Data 090319
U.S. Environmental Protection Agency —
Neurotox data on in silico predicted chemicals to cause protein adducts in peripheral neurons. Includes cytotoxicity (LDH release), changes in neuron network... -
Federal
Data for Tipping Point determinations
U.S. Environmental Protection Agency —
The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript.... -
Federal
Dataset for Saavedra et al.
U.S. Environmental Protection Agency —
Data in each figure of the publication are provided in different tabs of the excel spreadsheet. There were multiple concentrations tested, which are listed in the... -
Federal
Effects of an Environmentally-relevant Mixture of Pyrethroid Insecticides on Spontaneous Activity in Primary Cortical Networks on Microelectrode Arrays
U.S. Environmental Protection Agency —
This manuscript tests the hypothesis of dose additivity of an environmental mixture of pyrethriod insecticides at the level of network function, in vitro. The results... -
Federal
NHEERL MEA Toxcast Single Concentration Screening data
U.S. Environmental Protection Agency —
This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single... -
Federal
Provides an overview of the analysis and associated files, scripts and datasets
U.S. Environmental Protection Agency —
This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the... -
Federal
Data for Brown et al MEA Developmental Neurotoxicity Screening Manuscript
U.S. Environmental Protection Agency —
These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used.... -
Federal
In vitro screening of metal oxide nanoparticles for effects on neural function using cortical networks
U.S. Environmental Protection Agency —
Data describe the effects of metal oxide nanoparticles on total spikes and active electrodes after exposure to various concentrations for 1, 24 and 48 hrs, or after... -
Federal
Data set for Kosnik et al
U.S. Environmental Protection Agency —
The zip file contains all data and scripts used for the material presented in the manuscript by Kosnik et al. This dataset is associated with the following... -
Federal
Data for: Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays
U.S. Environmental Protection Agency —
This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on... -
Federal
Dataset for Chemical Signatures of neurodevelopmental disorders
U.S. Environmental Protection Agency —
This dataset contains the data, code and associated files for the manuscript Authored by Marable et al. This dataset is associated with the following publication:... -
Federal
MEA 86 Compound data
U.S. Environmental Protection Agency —
This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and...