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    • Data for: Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays

    Metadata Updated: November 12, 2020

    This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development measured in vitro. There are 17 parameters plus 2 measures of viability. In addition, the data for the ranking of potency and selectivity are provided, as well as data for the comparisons to other ToxCast assays and in vitro to in vivo extrapolations.

    This dataset is associated with the following publication: Shafer, T., J. Brown, B. Lynch, S. Davila-Montero, K. Wallace, and K. Paul-Friedman. Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 169(2): 436-455, (2019).

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

    Downloads & Resources

    References

    https://doi.org/10.1093/toxsci/kfz052

    Dates

    Metadata Created Date November 12, 2020
    Metadata Updated Date November 12, 2020

    Metadata Source

    Harvested from EPA ScienceHub

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date November 12, 2020
    Metadata Updated Date November 12, 2020
    Publisher U.S. EPA Office of Research and Development (ORD)
    Maintainer
    Identifier https://doi.org/10.23719/1503191
    Data Last Modified 2018-11-26
    Public Access Level public
    Bureau Code 020:00
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Harvest Object Id 950a8c3f-63fa-4b64-877d-382cffd8f177
    Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
    Harvest Source Title EPA ScienceHub
    License https://pasteur.epa.gov/license/sciencehub-license.html
    Program Code 020:095
    Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
    Related Documents https://doi.org/10.1093/toxsci/kfz052
    Source Datajson Identifier True
    Source Hash 259daded8a0073be902d70a31a9c93499428bc8c
    Source Schema Version 1.1

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