Data for: Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays

Metadata Updated: June 27, 2019

This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development measured in vitro. There are 17 parameters plus 2 measures of viability. In addition, the data for the ranking of potency and selectivity are provided, as well as data for the comparisons to other ToxCast assays and in vitro to in vivo extrapolations.

This dataset is associated with the following publication: Shafer, T., J. Brown, B. Lynch, S. Davila-Montero, K. Wallace, and K. Paul-Friedman. Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 169(2): 436-455, (2019).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

Downloads & Resources

References

https://dx.doi.org/10.1093/toxsci/kfz052

Dates

Metadata Created Date February 6, 2019
Metadata Updated Date June 27, 2019

Metadata Source

Harvested from EPA ScienceHub

Additional Metadata

Resource Type Dataset
Metadata Created Date February 6, 2019
Metadata Updated Date June 27, 2019
Publisher U.S. EPA Office of Research and Development (ORD)
Unique Identifier https://doi.org/10.23719/1503191
Maintainer
Timothy Shafer
Maintainer Email
Public Access Level public
Bureau Code 020:00
Schema Version https://project-open-data.cio.gov/v1.1/schema
Harvest Object Id 6a64c24d-385f-4a62-8684-e248fc49be82
Harvest Source Id cf9b0004-f9fd-420e-bade-a86839e82acf
Harvest Source Title EPA ScienceHub
License https://pasteur.epa.gov/license/sciencehub-license.html
Data Last Modified 2018-11-26
Program Code 020:095
Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents https://dx.doi.org/10.1093/toxsci/kfz052
Source Datajson Identifier True
Source Hash 8e0e61450b6ac3388b46ebdc178fdfe4fc611fd9
Source Schema Version 1.1

Didn't find what you're looking for? Suggest a dataset here.