14 datasets found
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Federal
Data for: Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays
U.S. Environmental Protection Agency —
This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on... -
Federal
Raw Data for Jarema et al, 2022 Developmental Neurotoxicity and Behavioral Screening in Larval Zebrafish...
U.S. Environmental Protection Agency —
The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics10050256/s1. Figure S1, Effect of DMSO on Light/Dark Locomotor... -
Federal
Data for Tipping Point determinations
U.S. Environmental Protection Agency —
The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript.... -
Federal
Moser_NTT_52:2015
U.S. Environmental Protection Agency —
data supporting manuscript figures. This dataset is associated with the following publication: Moser , V.C., P. Phillips , J. Hedge , and K. Mcdaniel.... -
Federal
Doc Title: Adult Hippocampal Neurogenesis is Impaired by Transient Developmental Thyroid Hormone Disruption
U.S. Environmental Protection Agency —
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis... -
Federal
This file contains data used to generate figures shown in Phelps et al. Microbial colonization is required for normal neurobehavioral development in zebrafish. Scientific Reports. 2017.
U.S. Environmental Protection Agency —
Data used to generate figures shown in Phelps et al. This dataset is associated with the following publication: Phelps, D., N. Brinkman, S. Keely, E. Anneken, T.... -
Federal
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network
U.S. Environmental Protection Agency —
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data... -
Federal
PBPK_modeloutputs_readme
U.S. Environmental Protection Agency —
Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A.... -
Federal
Neurite outgrowth in human iPSC-derived neurons
U.S. Environmental Protection Agency —
Data on morphology of rat and human neurons in cell culture. This dataset is associated with the following publication: Druwe, I., T. Freudenrich , K. Wallace , T.... -
Federal
Beasley_Impacts of a perinatal exposure to manganese coupled with maternal stress in rats: Maternal somatic measures and the postnatal growth and development of rat offspring_data_V1
U.S. Environmental Protection Agency —
Data set for the neurodevelopmental and somatic impacts of a perinatal exposure to stress coupled with Mn exposure on dams and their offspring. This dataset is... -
Federal
Provides an overview of the analysis and associated files, scripts and datasets
U.S. Environmental Protection Agency —
This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the... -
Federal
MEA 86 Compound data
U.S. Environmental Protection Agency —
This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and... -
Federal
Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity
U.S. Environmental Protection Agency —
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis,... -
Federal
Data for Brown et al MEA Developmental Neurotoxicity Screening Manuscript
U.S. Environmental Protection Agency —
These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used....
14 datasets found