-
Federal
Consumer Product Category Database recent views
U.S. Environmental Protection Agency —
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use... -
Federal
Datasets associated with journal article 'Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example' by Nyffeler, J, et.al. recent views
U.S. Environmental Protection Agency —
We evaluated the Templated Oligo with Sequencing Readout (TempO-Seq) assay for High-throughput transcriptomic screening of a small set of environmental chemicals.... -
Federal
Exposure Forecaster recent views
U.S. Environmental Protection Agency —
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure... -
Federal
Interactive Chemical Safety for Sustainablity Toxicity Forecaster Dashboard recent views
U.S. Environmental Protection Agency —
EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800... -
Federal
ToxCast Phase I recent views
U.S. Environmental Protection Agency —
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental... -
Federal
Aggregated Computational Toxicology Online Resource recent views
U.S. Environmental Protection Agency —
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from... -
Federal
High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells recent views
U.S. Environmental Protection Agency —
Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'. -
Federal
RJudson_Mansouri_CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity recent views
U.S. Environmental Protection Agency —
Data and supplemental files from COMPARA (A large-scale modeling project). COMPARA combined multiple models developed in collaboration with modelers and computational... -
Federal
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry recent views
U.S. Environmental Protection Agency —
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content... -
Federal
Data supporting amphibian thyroid model parameterization recent views
U.S. Environmental Protection Agency —
This dataset was generated to support parameterization of a larval amphibian thyroid axis computational model. Specifically, plasma iodine levels were determined not... -
Federal
Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay recent views
U.S. Environmental Protection Agency —
Cell Painting is a high-throughput, phenotypic profiling assay that uses fluorescent cytochemistry o visualize a variety of organelles and high-content imaging to... -
Federal
Concentrations of Pesticides, Pharmaceuticals, Organic Waste Indicators, and Volatile Organic Chemical Contaminants and Their Predicted Effects Potential in Wadeable Southeastern USA Streams recent views
Department of the Interior —
This dataset presents the results of 475 unique organic compounds collected from 54 wadeable streams within the Southeastern, USA, collected within 10 weeks during... -
Federal
Grulke_EPA’s DSSTox Chemical Structure Database recent views
U.S. Environmental Protection Agency —
The US Environmental Protection Agency’s (EPA) Distributed Structure-Searchable Toxicity (DSSTox) database, launched publicly in 2004, currently exceeds 875 K... -
Federal
SEQUENCING AND DE NOVO DRAFT ASSEMBLIES OF A FATHEAD MINNOW (Pimpehales promelas) reference genome recent views
U.S. Environmental Protection Agency —
The dataset provides the URLs for accessing the genome sequence data and two draft assemblies as well as fathead minnow genotyping data associated with estimating the... -
Federal
Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening recent views
U.S. Environmental Protection Agency —
Dataset for article ‘Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity... -
Federal
Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data recent views
U.S. Environmental Protection Agency —
** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or... -
Federal
Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program recent views
U.S. Environmental Protection Agency —
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the... -
Federal
Pilot testing and optimization of a larval fathead minnow high throughput transcriptomics assay recent views
U.S. Environmental Protection Agency —
The present study describes pilot testing of a high throughput compatible transcriptomics assay with larval fathead minnows. One day post hatch fathead minnows were... -
Federal
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network recent views
U.S. Environmental Protection Agency —
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data... -
Federal
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space recent views
U.S. Environmental Protection Agency —
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here,...