22 datasets found
-
Federal
Gestational Exposure to Perchlorate in the rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain recent views
U.S. Environmental Protection Agency —
This dataset contains results from rodent study. Thyroid hormones and brain endpoints are reported for pregnant rat dams and progeny on gestational day 20 following... -
Federal
Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption recent views
U.S. Environmental Protection Agency —
The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database... -
Federal
WM_betasdam Final data and code recent views
U.S. Environmental Protection Agency —
Hydrological, biological, geomorphological, and geospatial datasets collected from the Western Mountains of the United States used to develop the beta SDAM for the... -
Federal
Verification of in vivo estrogenic activity for four per- and polyfluoroalkyl substances (PFAS) identified as estrogen receptor agonists via new approach methodologies (v4) recent views
U.S. Environmental Protection Agency —
The dataset includes data from six experiments in which adult male fathead minnows were exposed to five concentrations of a per- or polyfluorinated alkyl substance... -
Federal
Developmental toxicity of PFO4DA and PFO5DoA assessed using hepatic transcriptomics and serum metabolomics recent views
U.S. Environmental Protection Agency —
Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the... -
Federal
Transcriptomic data (GSE199233) and CEBs data (from Blake et al. 2020) for maternal and fetal endpoints following gestational exposure to PFOA or GenX recent views
U.S. Environmental Protection Agency —
Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA)... -
Federal
DINP VS T PROD AND INSL3 DOSE RESPONSE 2023 recent views
U.S. Environmental Protection Agency —
DATA USED IN PAPER. This dataset is associated with the following publication: Gray, L. Biologically relevant reductions in fetal testosterone and Insl3 induced by in... -
Federal
Evans_2022_PFAS_in-vitro_manuscript_ScienceHub_2022-6-24 recent views
U.S. Environmental Protection Agency —
Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma... -
Federal
Dataset for Publication PFAS Modulate Osmotic Signaling Independent of Gravimetric Changes in the Rat Uterus recent views
U.S. Environmental Protection Agency —
Uterotrophic assay data analysis from gene arrays and uterine weights. This dataset is associated with the following publication: Dixon, A., E. Rowan, A. Yackley, and... -
Federal
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network recent views
U.S. Environmental Protection Agency —
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data... -
Federal
Case study in 21st century ecotoxicology: Using in vitro aromatase inhibition data to predict reproductive outcomes in fish, in vivo. recent views
U.S. Environmental Protection Agency —
Data set includes empirical results from 60 h, 10 d, and 21 d exposures of female fathead minnows to the fungicide imazalil as well as simulations from predictive... -
Federal
Data for Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish recent views
U.S. Environmental Protection Agency —
The data set includes: 1) Swimbladder inflation at 120 hours post-fertilization (hpf) 2) Swimbladder surface area at 120 hpf 3) Larval body length at 120 hpf 4)... -
Federal
ToxCast data and SeqAPASS results related to case study chemicals and targets referenced in Leveraging New Approach Methodologies to Complement Aquatic Life Criteria Derivation recent views
U.S. Environmental Protection Agency —
Excel file containing ToxCast bioactivity data for carbaryl, celecoxib, chromium triacetate, HgCl2, nonylphenol, pentachlorophenol, PFOA, PFOS, pioglitazone, sodium... -
Federal
Mussel shell weight, Mussel survival rate recent views
U.S. Environmental Protection Agency —
Mussel shell weight, Mussel survival rate. This dataset is not publicly accessible because: Data is the property of Dr. Sean Collins, Division of Plant & Soil... -
Federal
MS Datasets and Analyses for Shenandoah River FHM Metabolomics recent views
U.S. Environmental Protection Agency —
MS Datasets and Analyses for Shenandoah River FHM Metabolomics -
Federal
Methods for Thyroid Hormone Measurements in Neonatal Rat Brain recent views
U.S. Environmental Protection Agency —
Serum and brain thyroid hormone measurements in rat brain. This dataset is associated with the following publication: Gilbert, M., J. Ford, C. Riutta, K.... -
Federal
Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat data set recent views
U.S. Environmental Protection Agency —
Data set contains summary data (mean, standard error, sample size) for all measured endpoints from all experiments reported in the published manuscript. This dataset... -
Federal
Structural Malformations in Brain Accompany Developmental Perchlorate Exposure in Rodents recent views
U.S. Environmental Protection Agency —
Structural defects in the rat brain associated with maternal exposure to ammonium perchlorate accompanied reductions in circulating levels of thyroid hormone in the... -
Federal
Effects of the diphenyl herbicide, oxyfluorfen, on thyroid hormones in the juvenile rat following 4- and 8-day exposure.. recent views
U.S. Environmental Protection Agency —
Data on hormone and chemical analysis is included for the effects of oxyfluorfen on thyroid hormones in the 4- and 8-day exposed juvenile rats. This dataset is... -
Federal
Raw data presented in manuscript "The Pollutant Perfluorohexane Sulfonate (PFHxS) Reduces Serum Thyroxine but Does Not Alter Thyroid Hormone Action in the Postnatal Rat Brain" by O'Shaughnessy et al. 2024. recent views
U.S. Environmental Protection Agency —
Raw data to accompanying manuscript "The Pollutant Perfluorohexane Sulfonate (PFHxS) Reduces Serum Thyroxine but Does Not Alter Thyroid Hormone Action in the...
22 datasets found