ToxCast data and SeqAPASS results related to case study chemicals and targets referenced in Leveraging New Approach Methodologies to Complement Aquatic Life Criteria Derivation
Excel file containing ToxCast bioactivity data for carbaryl, celecoxib, chromium triacetate, HgCl2, nonylphenol, pentachlorophenol, PFOA, PFOS, pioglitazone, sodium dichromate, TCDD.
The .zip file contains SeqAPASS results for multiple protein targets.
This dataset is associated with the following publication:
Schaupp, C., C. Lalone, B. Blackwell, G. Ankley, and D. Villeneuve. Leveraging ToxCast data and protein sequence conservation to complement aquatic life criteria derivation. Integrated Environmental Assessment and Management. Allen Press, Inc., Lawrence, KS, USA, 19(1): 224-238, (2023).
Resources
2 resources available
-
OW NAMs Case Study_ToxCast Data for Science Hub.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET -
OW NAMs_SeqAPASS Data for Science Hub.zip
APPLICATION/X-ZIP-COMPRESSED
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Daniel Villeneuve", "hasEmail": "mailto:villeneuve.dan@epa.gov" } |
| description | Excel file containing ToxCast bioactivity data for carbaryl, celecoxib, chromium triacetate, HgCl2, nonylphenol, pentachlorophenol, PFOA, PFOS, pioglitazone, sodium dichromate, TCDD. The .zip file contains SeqAPASS results for multiple protein targets. This dataset is associated with the following publication: Schaupp, C., C. Lalone, B. Blackwell, G. Ankley, and D. Villeneuve. Leveraging ToxCast data and protein sequence conservation to complement aquatic life criteria derivation. Integrated Environmental Assessment and Management. Allen Press, Inc., Lawrence, KS, USA, 19(1): 224-238, (2023). |
| distribution |
[ { "title": "OW NAMs Case Study_ToxCast Data for Science Hub.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524425/OW%20NAMs%20Case%20Study_ToxCast%20Data%20for%20Science%20Hub.xlsx" }, { "title": "OW NAMs_SeqAPASS Data for Science Hub.zip", "mediaType": "application/x-zip-compressed", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524425/OW%20NAMs_SeqAPASS%20Data%20for%20Science%20Hub.zip" } ] |
| identifier | https://doi.org/10.23719/1524425 |
| keyword |
[ "Adverse Outcome Pathways (AOPs)", "New Approach Methods (Alternatives to Animal Testi", "ToxCast", "aquatic life criteria", "new approach methodologies" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2021-12-06 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1002/ieam.4617" ] |
| rights |
null
|
| title | ToxCast data and SeqAPASS results related to case study chemicals and targets referenced in Leveraging New Approach Methodologies to Complement Aquatic Life Criteria Derivation |
