11 datasets found
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Federal
Adrenergic receptor subtypes differentially influence acrolein-induced ventilatory, vascular leakage, and inflammatory responses
U.S. Environmental Protection Agency —
Individual sample data for each figure in exscel file. This dataset is associated with the following publication: Alewel, D., S. Gavett, K. Rentschler, M.... -
Federal
Ambient Particulate Matter and Acrolein Co-Exposure Increases Myocardial Dyssynchrony in Mice via TRPA1
U.S. Environmental Protection Agency —
We have examined the potential for interactive cardiovascular effects of repeated, intermittent co-exposure to concentrated ambient particulate matter (CAPs) and... -
Federal
Sex-specific respiratory and systemic stress effects of acute acrolein and trichloroethylene inhalation
U.S. Environmental Protection Agency —
Employing acrolein, a potent airway irritant, and TCE, with low irritancy, authors hypothesized that airway injury and inflammation would be involved in eliciting... -
Federal
Estrogen and glucocorticoid receptors co-regulate acrolein-induced respiratory and systemic homeostatic stress responses
U.S. Environmental Protection Agency —
Excel file containing individual data points for all figures and tables in the manuscript. -
Federal
Serum metabolome and liver transcriptome reveal acrolein inhalation-induced sex-specific homeostatic dysfunction
U.S. Environmental Protection Agency —
Excel file of all data pertaining to the manuscript. It contains metabolomic and genomic data with GEO number for the given study. This dataset is associated with the... -
Federal
Cardiac effects of acrolein in mice and role of TRPA1
U.S. Environmental Protection Agency —
This data shows the heart rate, heart rate variability and cardiac mechanical function of mice exposed to acrolein or ozone. This dataset is associated with the... -
Federal
Acrolein inhalation acutely affects the regulation of mitochondrial metabolism in rat lung
U.S. Environmental Protection Agency —
Exposure of the airways to cigarette smoke (CS) is the primary risk factor for developing several lung diseases such as Chronic Obstructive Pulmonary Disease (COPD).... -
Federal
Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats
U.S. Environmental Protection Agency —
Frontiers in Toxicology paper, Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats, 2023 Alewel DI. This dataset is... -
Federal
Acrolein Inhalation Alters Myocardial Synchrony and Performance at and Below Exposure Concentration that Cause Ventilatory Responses in Mice
U.S. Environmental Protection Agency —
we examined the cardiovascular effects acrolein inhalation, particularly on myocardial synchrony and performance via ultrasound echocardiography. Male C57Bl/6J mice... -
Federal
Validation of a Novel Cell Culture Exposure System (CCES) for Studying the Toxicity of Volatile Chemicals at the Air-Liquid Interface
U.S. Environmental Protection Agency —
We developed a cell culture exposure system (CCES) to expose cells at the air-liquid interface (ALI) to volatile chemicals. We characterized the CCES by exposing... -
Federal
Respiratory Effects and Systemic Stress Response Following Acute Acrolein Inhalation in Rats
U.S. Environmental Protection Agency —
This data set is an Excel file pertaining to the study that examined nasal, pulmonary, and systemic effects of acrolein in rats acutely exposed to a range of...
11 datasets found