-
Federal
An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use
U.S. Department of Health & Human Services —
Background Management of thalassemia major requires patients to have life-long access to a treatment regimen of regular blood transfusions coupled with iron chelation... -
Federal
Debate: A subversive view of subsets - a dissident clinician's opinion
U.S. Department of Health & Human Services —
Clinical trialists and statisticians are very wary of subgroup analysis, for good reasons. Clinicians have to deal with situations in which subgroups of patients... -
Federal
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
U.S. Department of Health & Human Services —
Background An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to... -
Federal
Time course of muscle soreness following different types of exercise
U.S. Department of Health & Human Services —
Background Post-exercise muscle soreness is a dull, aching sensation that follows unaccustomed muscular exertion. Primarily on the basis of previous laboratory-based... -
Federal
Long-term resource variation and group size: A large-sample field test of the Resource Dispersion Hypothesis
U.S. Department of Health & Human Services —
Background The Resource Dispersion Hypothesis (RDH) proposes a mechanism for the passive formation of social groups where resources are dispersed, even in the absence... -
Federal
Organization specific predictors of job satisfaction: findings from a Canadian multi-site quality of work life cross-sectional survey
U.S. Department of Health & Human Services —
Background Organizational features can affect how staff view their quality of work life. Determining staff perceptions about quality of work life is an important... -
Federal
Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
U.S. Department of Health & Human Services —
Several recent papers have shown that both familial primary pulmonary hypertension (FPPH) and sporadic primary pulmonary hypertension (PPH) may have a common etiology... -
Federal
Why the fair innings argument is not persuasive
U.S. Department of Health & Human Services —
The fair innings argument (FIA) is frequently put forward as a justification for denying elderly patients treatment when they are in competition with younger patients... -
Federal
Drug-induced and postnatal hypothyroidism impairs the accumulation of diacylglycerol in liver and liver cell plasma membranes
U.S. Department of Health & Human Services —
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC)... -
Federal
Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40)
U.S. Department of Health & Human Services —
Background SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been... -
Federal
The use of breast conserving surgery: linking insurance claims with tumor registry data
U.S. Department of Health & Human Services —
Background The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with... -
Federal
Regular use of aspirin and pancreatic cancer risk
U.S. Department of Health & Human Services —
Background Regular use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been consistently associated with reduced risk of colorectal cancer and... -
Federal
What you should know about PR3-ANCA: Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA
U.S. Department of Health & Human Services —
The neutrophil azurophil granule constituent proteinase 3 (PR3) is the principal antigen for anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's... -
Federal
In what extent anemia coexists with cognitive impairment in elderly: a cross-sectional study in Greece
U.S. Department of Health & Human Services —
Background A project aimed at studying the frequency of dementia and depression in the catchment area of the Health Centre of Chrissoupolis (HCCh), Northern Greece,... -
Federal
Medical immunology: a new journal for a new subspecialty
U.S. Department of Health & Human Services —
Medical immunology: a new journal for a new subspecialty -
Federal
Identification of stem cell units in the terminal end bud and duct of the mouse mammary gland
U.S. Department of Health & Human Services —
The mouse mammary gland may undergo cycles of proliferation, terminal differentiation, tissue remodeling, and more importantly malignant transformation. Mammary... -
Federal
Splinting or surgery for carpal tunnel syndrome? Design of a randomized controlled trial [ISRCTN18853827]
U.S. Department of Health & Human Services —
Background Carpal tunnel syndrome is a common disorder, which can be treated with surgery or conservative options. However, there is insufficient evidence and no... -
Federal
Increased risk of traffic accidents in subjects with latent toxoplasmosis: a retrospective case-control study
U.S. Department of Health & Human Services —
Background The parasite Toxoplasma gondii infects 30–60% of humans worldwide. Latent toxoplasmosis, i.e., the life-long presence of Toxoplasma cysts in neural and... -
Federal
B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus
U.S. Department of Health & Human Services —
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the... -
Federal
Evolution of gene fusions: horizontal transfer versus independent events
U.S. Department of Health & Human Services —
Background Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution,...