27 datasets found
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Federal
Diuretics: again the first step in the treatment of most patients with hypertension
U.S. Department of Health & Human Services —
The results and interpretations of the most recent controlled clinical trials on antihypertensive drugs have fuelled the debate about the drug that should be used to... -
Federal
Systematic reviews of complementary therapies – an annotated bibliography. Part 3: Homeopathy
U.S. Department of Health & Human Services —
Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical... -
Federal
Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!
U.S. Department of Health & Human Services —
Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power,... -
Federal
Selected highlights from the 50
U.S. Department of Health & Human Services —
The recent scientific session of the American College of Cardiology (ACC), held in Orlando, provided a forum for ongoing cardiovascular clinical trials from around... -
Federal
Do multiple outcome measures require p-value adjustment?
U.S. Department of Health & Human Services —
Background Readers may question the interpretation of findings in clinical trials when multiple outcome measures are used without adjustment of the p-value. This... -
Federal
Fundamental deficiencies in the megatrial methodology
U.S. Department of Health & Human Services —
The fundamental methodological deficiency of megatrials is deliberate reduction of experimental control in order to maximize recruitment and compliance of subjects.... -
Federal
Systematic reviews of complementary therapies – an annotated bibliography. Part 2: Herbal medicine
U.S. Department of Health & Human Services —
Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical...
27 datasets found