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Federal
Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
U.S. Department of Health & Human Services —
Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has... -
Federal
The evaluation of yeast derivatives as adjuvants for the immune response to the Bm86 antigen in cattle
U.S. Department of Health & Human Services —
Background The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this... -
Federal
Cloning and expression of the rabbit prostaglandin EP2 receptor
U.S. Department of Health & Human Services —
Background Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence... -
Federal
The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
U.S. Department of Health & Human Services —
Background The human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4... -
Federal
Conceptual framework of public health surveillance and action and its application in health sector reform
U.S. Department of Health & Human Services —
Background Because both public health surveillance and action are crucial, the authors initiated meetings at regional and national levels to assess and reform... -
Federal
The association between secondhand smoke and the risk of developing acute coronary syndromes, among non-smokers, under the presence of several cardiovascular risk factors: The CARDIO2000 case-control study
U.S. Department of Health & Human Services —
Background The purpose of this study was to investigate the association between secondhand smoke and the risk of developing a first event of acute coronary syndromes... -
Federal
Long term benzodiazepine use for insomnia in patients over the age of 60: discordance of patient and physician perceptions
U.S. Department of Health & Human Services —
Background The aim of this study was to determine and compare patients' and physicians' perceptions of benefits and risks of long term benzodiazepine use for insomnia... -
Federal
Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002
U.S. Department of Health & Human Services —
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem... -
Federal
Survey of the knowledge, attitude and practice of Nigerian surgery trainees to HIV-infected persons and AIDS patients
U.S. Department of Health & Human Services —
Background The incidence of HIV infection and AIDS is rising in Nigeria. Surgeons are at risk of occupationally acquired infection as a result of intimate contact... -
Federal
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
U.S. Department of Health & Human Services —
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however... -
Federal
A mathematical model of optimized radioiodine-131 therapy of Graves' hyperthyroidism
U.S. Department of Health & Human Services —
Background The current status of radioiodine-131 (RaI) dosimetry for Graves' hyperthyroidism is not clear. Recurrent hyperthyroidism and iatrogenic hypothyroidism are... -
Federal
Plasma colloid osmotic pressure in healthy infants
U.S. Department of Health & Human Services —
Background The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants... -
Federal
Heart rate changes during partial seizures: A study amongst Singaporean patients
U.S. Department of Health & Human Services —
Introduction Studies in Europe and America showed that tachycardia, less often bradycardia, frequently accompanied partial seizures in Caucasian patients. We... -
Federal
A successful pregnancy following SEM fine tuning of hormonal priming
U.S. Department of Health & Human Services —
Background Manipulation of the uterine epithelium utilising standard dose exogenous oestrogen (E2) and progesterone (P4) has been shown to achieve a mature secretory... -
Federal
Molecular action of methotrexate in inflammatory diseases
U.S. Department of Health & Human Services —
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed... -
Federal
Effects of de-industrialization on unemployment, re-employment, and work conditions in a manufacturing workforce
U.S. Department of Health & Human Services —
Background The purpose of this study was to investigate the impact of a 20-year process of de-industrialization in the British Columbia (BC) sawmill industry on... -
Federal
Food intakes and preferences of hospitalised geriatric patients
U.S. Department of Health & Human Services —
Background A cross sectional survey was carried out on 120 hospitalised geriatric patients aged 60 and above in Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur... -
Federal
Where is biological therapy going?
U.S. Department of Health & Human Services —
The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets... -
Federal
Modeling of failure mode in knee ligaments depending on the strain rate
U.S. Department of Health & Human Services —
Background The failure mechanism of the knee ligament (bone-ligament-bone complex) at different strain rates is an important subject in the biomechanics of the knee.... -
Federal
Therapy of ankylosing spondylitis and other spondyloarthritides: established medical treatment, anti-TNF-α therapy and other novel approaches
U.S. Department of Health & Human Services —
Therapeutic options for patients with more severe forms of spondyloarthritis (SpA) have been rather limited in recent decades. There is accumulating evidence that...