288 datasets found
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Federal
Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress related damage in the murine retina (RR-9)
National Aeronautics and Space Administration —
Extended spaceflight has been shown to adversely affect astronaut visual acuity. The purpose of this study was to determine whether spaceflight alters gene expression... -
Federal
Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids - Drosophila data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Spaceflight adaptation requires organ specific alterations in the proteomes of Arabidopsis
National Aeronautics and Space Administration —
Life in spaceflight demonstrates remarkable adaptive processes within the specialized environments of space vehicles which are subject to the myriad of attending and... -
Federal
A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space
National Aeronautics and Space Administration —
Bacterial behavior has been observed to change during spaceflight. Higher final cell counts, enhanced biofilm formation, increased virulence, and reduced... -
Federal
Rodent Research-3-CASIS: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays
National Aeronautics and Space Administration —
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays, or 10 cGy or 30 cGy densely ionizing... -
Federal
Transcriptomics analysis of etiolated Arabidopsis thaliana seedlings in response to microgravity
National Aeronautics and Space Administration —
Gene expression profile of two-week-old etiolated Arabidopsis seedlings under microgravity on board space flight BRIC16 were compared with ground grown control in... -
Federal
Evaluation of in vitro macrophage differentiation during space flight
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth
National Aeronautics and Space Administration —
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness... -
Federal
Genome sequencing of Staphylococcus, Burkholderia, and Ralstonia bacterial isolates isolated from the ISS
National Aeronautics and Space Administration —
This repository holds genome assemblies for Staphylococcus, Burkholderia, and Ralstonia bacterial isolates isolated from the ISS between the years of 2006-2015.... -
Federal
Transcriptional profiling of adrenal glands from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
Draft Genome Sequences of novel Agrobacterium genomospecies 3 Associated from the International Space Station
National Aeronautics and Space Administration —
The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being... -
Federal
Integrative Transcriptomics and Proteomics Profiling of Arabidopsis thaliana Elucidates Novel Mechanisms Underlying Spaceflight Adaptation
National Aeronautics and Space Administration —
Spaceflight presents a unique environment with complex stressors, including microgravity and radiation, that can influence plant physiology at molecular levels.... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root, hypocotyl and shoot responses to the orbital environment
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 2]
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses... -
Federal
Biological Research in Canisters-16 (BRIC-16): Transcriptomics, Glycomics, and Morphometric photography.
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Drosophila melanogaster gene expression changes after spaceflight.
National Aeronautics and Space Administration —
Gene expression levels were determined in 3rd instar and adult Drosophila melanogaster reared during spaceflight, to elucidate the genetic and molecular mechanisms... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Transcriptional profiling of mammary glands from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), also known as RR-8, forty female BALB/cAnNTac mice were flown on the International Space Station. To assess...
288 datasets found