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Federal
Impact of obesity on glucose and lipid profiles in adolescents at different age groups in relation to adulthood
U.S. Department of Health & Human Services —
Background As obesity is rapidly becoming a major medical and public health problem, the aim of our study was to determine: 1) if obesity in Caucasian adolescents at... -
Federal
Internet hand x-rays: A comparison of joint space narrowing and erosion scores (Sharp/Genant) of plain versus digitized x-rays in rheumatoid arthritis patients
U.S. Department of Health & Human Services —
Background The objective of the study is to examine the reliability of erosion and joint space narrowing scores derived from hand x-rays posted on the Internet... -
Federal
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
U.S. Department of Health & Human Services —
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however... -
Federal
Genetic epidemiology: Systemic lupus erythematosus
U.S. Department of Health & Human Services —
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies... -
Federal
Problems in early diagnosis of bladder cancer in a spinal cord injury patient: Report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder
U.S. Department of Health & Human Services —
Background Typical symptoms and signs of a clinical condition may be absent in spinal cord injury (SCI) patients. Case presentation A male with paraplegia was passing... -
Federal
Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome
U.S. Department of Health & Human Services —
Background In humans, there are four alkaline phosphatases, and each form exibits a characteristic pattern of tissue distribution. The availability of an easy method... -
Federal
Dorsal horn-enriched genes identified by DNA microarray, in situ hybridization and immunohistochemistry
U.S. Department of Health & Human Services —
Background Neurons in the dorsal spinal cord play important roles in nociception and pain. These neurons receive input from peripheral sensory neurons and then... -
Federal
VirOligo: a database of virus-specific oligonucleotides
U.S. Department of Health & Human Services —
VirOligo is a database of virus-specific oligonucleotides. The VirOligo database consists of two tables, Common data and Oligo data. The Oligo data table contains PCR... -
Federal
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer
U.S. Department of Health & Human Services —
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in... -
Federal
Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
U.S. Department of Health & Human Services —
Background Health Related Quality of Life (HRQoL) is an important outcome measure in Inflammatory Bowel Disease (IBD). The aim of our study was to assess HRQoL in a... -
Federal
Linkage analysis of HLA and candidate genes for celiac disease in a North American family-based study
U.S. Department of Health & Human Services —
Background Celiac disease has a strong genetic association with HLA. However, this association only explains approximately half of the sibling risk for celiac... -
Federal
Cellular senescence:ex vivop53-dependent asymmetric cell kinetics
U.S. Department of Health & Human Services —
Cellular senescence is a defining property of euploid cells in culture [1,2]. Cultures derived from cells explanted from tissues of a variety of animal species... -
Federal
Safety of a new extensively hydrolysed formula in children with cow's milk protein allergy: a double blind crossover study
U.S. Department of Health & Human Services —
Background Formulae for infants with cow's milk protein allergy (CMA) should be based on extensively hydrolysed protein. 'Extensively' however is not strictly... -
Federal
Phospholipase Cδ regulates germination of
U.S. Department of Health & Human Services —
Background Many eukaryotes, including plants and fungi make spores that resist severe environmental stress. The micro-organism Dictyostelium contains a single... -
Federal
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures
U.S. Department of Health & Human Services —
Background Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report... -
Federal
Accessing and distributing EMBL data using CORBA (common object request broker architecture)
U.S. Department of Health & Human Services —
Background: The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences and related information traditionally made available in flat-... -
Federal
Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
U.S. Department of Health & Human Services —
Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has... -
Federal
Conceptual framework of public health surveillance and action and its application in health sector reform
U.S. Department of Health & Human Services —
Background Because both public health surveillance and action are crucial, the authors initiated meetings at regional and national levels to assess and reform... -
Federal
A clustering method for repeat analysis in DNA sequences
U.S. Department of Health & Human Services —
Background A computational system for analysis of the repetitive structure of genomic sequences is described. The method uses suffix trees to organize and search the... -
Federal
Early glandular neoplasia of the lung
U.S. Department of Health & Human Services —
Although bronchogenic carcinomas progress through a very well defined sequence of metaplasia, dysplasia and carcinoma in situ, very little is known about the early...