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Federal
Transcriptional profiling of cerebellums from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
STS-135: Mouse Liver Transcriptomics using RNA-Seq
National Aeronautics and Space Administration —
Female C57BL/6CR mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in... -
Federal
New insights into the role of lncRNA after spaceflight
National Aeronautics and Space Administration —
We analyzed the transcriptional profile by RNA-sequencing of exosomal content isolated from blood plasma of three astronauts who flew on various ISS missions between... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina boulardi 17 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Relevance of Unfolded Protein Response to Spaceflight-Induced Transcriptional Reprogramming in Arabidopsis
National Aeronautics and Space Administration —
Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human... -
Federal
Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight: Advanced Plant EXperiment (APEX) 03-1 Raw Dataset
National Aeronautics and Space Administration —
This study was conducted to uncover the underlying molecular mechanisms by which microgravity impacts cell wall architecture in the model plant Arabidopsis thaliana... -
Federal
STS-135 Liver Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
Expression data from drosophila melanogaster
National Aeronautics and Space Administration —
Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term... -
Federal
Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight from RR-1 and RR-9 (calcium uptake and Western blot in soleus and tibialis anterior)
National Aeronautics and Space Administration —
It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a... -
Federal
Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space
National Aeronautics and Space Administration —
To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural... -
Federal
Spaceflight effects on the mouse retina: Histological, gene expression and epigenetic changes after flight on STS-135
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Transcriptomic response of Drosophila melanogaster pupae developed in hypergravity
National Aeronautics and Space Administration —
Physical forces greatly influence the growth and function of an organism. Altered gravity can perturb normal development and induce corresponding changes in gene... -
Federal
Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA, DNA, and protein were purified... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface, Kirovograd region soil, Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight
National Aeronautics and Space Administration —
The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe, non-invasive, daily... -
Federal
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight
National Aeronautics and Space Administration —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
Federal
Comparative Genomic Analysis of Klebsiella Exposed to Various Space Conditions at the International Space Station
National Aeronautics and Space Administration —
Due to the bacteria's evolved resistance to radiation, Klebsiella poses a great threat to not only planetary protection, but also to the integrity of future...