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    • Expression data from drosophila melanogaster

    Metadata Updated: August 30, 2025

    Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term exposure to the conditions of spaceflight. To understand these consequences better and to contribute to design of effective countermeasures, we used the Drosophila model to compare innate immune responses to bacteria and fungi in flies that were either raised on earth or in outer space aboard the NASA Space Shuttle Discovery (STS-121). Microarrays were used to characterize changes in gene expression that occur in response to infection by bacteria and fungus in drosophila that were either hatched and raised in outer space (microgravity) or on earth (normal gravity). Whole Oregon R strain drosophila melanogaster fruit flies either raised on earth or in space that were (1) uninfected, (2) infected with bacteria (Escherichia coli), or (3) infected with fungus (Beauveria bassiana) were used for RNA extraction and hybridization on Affymetrix microarrays.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

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    Dates

    Metadata Created Date April 11, 2025
    Metadata Updated Date August 30, 2025

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date April 11, 2025
    Metadata Updated Date August 30, 2025
    Publisher Open Science Data Repository
    Maintainer
    Identifier 10.25966/t6db-f633
    Data Last Modified 2025-08-21
    Category Biological and Physical Sciences
    Public Access Level public
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id d21cafba-9804-4880-bf9c-ffc0c18af019
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://osdr.nasa.gov/bio/repo/data/missions/STS-121
    Program Code 026:000
    Source Datajson Identifier True
    Source Hash c2c68aecb26c09597ddac2addd4b82f8da7ccba6a5cc30fb7d54c68ba9ca2b81
    Source Schema Version 1.1

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