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Federal
Male Fathead Minnow Transcriptomes and Associated Chemical Analytes in Milwaukee Estuary System recent views
U.S. Environmental Protection Agency —
This dataset presents the full hepatic transcriptomes of fathead minnows (Pimephales promelas) caged for four days at multiple sites within the Milwaukee Estuary area... -
Federal
Toward an AOP Network-based tiered testing strategy for the assessment of thyroid hormone disruption recent views
U.S. Environmental Protection Agency —
No novel data were reported in association with this product. This dataset is not publicly accessible because: The associated publication is a review/forum-type... -
Federal
Effects of deiodinase inhibition on amphibian metamorphosis recent views
U.S. Environmental Protection Agency —
This dataset contains in vitro and in vivo biochemical and apical (i.e., growth/development) data pertaining to iodotyrosine deiodinase inhibition in the African... -
Federal
Identifying chemicals and mixtures of potential biological concern detected in passive samplers from Great Lakes tributaries using high-throughput data and biological pathways recent views
U.S. Environmental Protection Agency —
Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar... -
Federal
Raw Data for Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis recent views
U.S. Environmental Protection Agency —
Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so... -
Federal
The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish recent views
U.S. Environmental Protection Agency —
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase... -
Federal
Conversion of environmental estrone to estradiol by male fathead minnows recent views
U.S. Environmental Protection Agency —
This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations... -
Federal
Integrative computational approaches to inform relative bioaccumulation potential of per- and polyfluoroalkyl substances (PFAS) across species recent views
U.S. Environmental Protection Agency —
Datasets included in the entry are Results from the US Environmental Protection Agency Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool and... -
Federal
Adverse outcome pathway recent views
U.S. Environmental Protection Agency —
cell culture information with toxicity and proteomic changes. This dataset is associated with the following publication: VanEmon, J., P. Pan, and F. Van Breukelen.... -
Federal
Data from "A method for CRISPR/Cas9 mutation of genes in fathead minnow (Pimephales promelas)" recent views
U.S. Environmental Protection Agency —
The dataset includes survival of control, control injected, and CRISPR/Cas9 injected embryos as well as percent efficiency of insertion/deletion mutation formation... -
Federal
Adverse Outcome Pathway Database (AOP-DB) version 2 recent views
U.S. Environmental Protection Agency —
The EPA has developed the Adverse Outcome Pathway Database (AOP-DB) to better characterize adverse outcomes of toxicological interest that are relevant to human... -
Federal
A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows recent views
U.S. Environmental Protection Agency —
The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR)... -
Federal
An Integrated Approach for Identifying Priority Contaminant in the Great Lakes Basin –Investigations in the Lower Green Bay/Fox River and Milwaukee Estuary Areas of Concern recent views
U.S. Environmental Protection Agency —
Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect... -
Federal
SEQUENCING AND DE NOVO DRAFT ASSEMBLIES OF A FATHEAD MINNOW (Pimpehales promelas) reference genome recent views
U.S. Environmental Protection Agency —
The dataset provides the URLs for accessing the genome sequence data and two draft assemblies as well as fathead minnow genotyping data associated with estimating the... -
Federal
A case study on the use of exposure-activity ratios (EARs) to prioritize sites, chemicals, and bioactivities of concern in Great Lakes waters recent views
U.S. Environmental Protection Agency —
As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity... -
Federal
Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity recent views
U.S. Environmental Protection Agency —
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to... -
Federal
Effects-based monitoring of bioactive compounds associated with municipal wastewater treatment plant effluent discharge to the South Platte River, Colorado, USA recent views
U.S. Environmental Protection Agency —
The datafile contains data associated with analytical chemistry, fish gene expression, in vitro bioassays, chemical prioritization, and Attagene data for surface... -
Federal
Maumee River 2012 and 2016 recent views
U.S. Environmental Protection Agency —
The Maumee River and associated tributaries are an example of a system influenced by a mosaic of contaminant inputs from point and nonpoint sources along a gradient... -
Federal
Adverse Outcome Pathway Networks I: Development and Applications recent views
U.S. Environmental Protection Agency —
In September, 2015, a water sample was collected downstream of a major metropolitan waste water treatment plant that discharges to the South Platte River, Colorado,...