Raw Data for Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis
Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly analyzed, once converted to individual comma-separated values (.csv) files, using the R code provided in Supplementary File 16. Column headings are described in the supplemental file 'Metadata Glossary.docx'.
This dataset is associated with the following publication:
Angrish, M., C. McQueen, E. Hubal, M. Bruno, Y. Ge, and B. Chorley. Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 159(1): 159-169, (2017).
Resources
2 resources available
-
Supp File 16.txt
TEXT/PLAIN -
Supporting_files_1-15.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Brian Chorley",
"hasEmail": "mailto:chorley.brian@epa.gov"
}
|
| description | Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly analyzed, once converted to individual comma-separated values (.csv) files, using the R code provided in Supplementary File 16. Column headings are described in the supplemental file 'Metadata Glossary.docx'. This dataset is associated with the following publication: Angrish, M., C. McQueen, E. Hubal, M. Bruno, Y. Ge, and B. Chorley. Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 159(1): 159-169, (2017). |
| distribution |
[
{
"title": "Supp File 16.txt",
"mediaType": "text/plain",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1376696/Supp%20File%2016.txt"
},
{
"title": "Supporting_files_1-15.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1376696/Supporting_files_1-15.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1376696 |
| keyword |
[
"adverse outcome pathway",
"chemical risk assessment",
"hepatic steatosis",
"high-throughput toxicity testing",
"mechanistic toxicology",
"non-alcoholic fatty liver disease"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2017-01-24 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1093/toxsci/kfx121",
"https://pasteur.epa.gov/uploads/10.23719/1376696/documents/Metadata%20Glossary.docx"
]
|
| rights |
null
|
| title | Raw Data for Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis |
