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Federal
Prevalence of hepatitis B and C markers in high-risk hospitalised patients in Crete: a five-year observational study
U.S. Department of Health & Human Services —
Background So far the prevalence of viral hepatitis infection in hospitalized patients has not been extensively studied. Therefore we conducted the present five-year... -
Federal
The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study
U.S. Department of Health & Human Services —
Background Many randomized trials involve measuring a continuous outcome - such as pain, body weight or blood pressure - at baseline and after treatment. In this... -
Federal
Evolutionary conservation of
U.S. Department of Health & Human Services —
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that... -
Federal
On the species of origin: diagnosing the source of symbiotic transcripts
U.S. Department of Health & Human Services —
Background Most organisms have developed ways to recognize and interact with other species. Symbiotic interactions range from pathogenic to mutualistic. Some... -
Federal
Gene expression neighborhoods
U.S. Department of Health & Human Services —
The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a... -
Federal
Detection ofMycobacterium avium subspecies paratuberculosisspecific IS900 insertion sequences in bulk-tank milk samples obtained from different regions throughout Switzerland
U.S. Department of Health & Human Services —
SinceMycobacterium aviumsubspeciesparatuberculosis(MAP) was isolated from intestinal tissue of a human patient suffering Crohn's disease, a controversial discussion... -
Federal
Rhythmic expression of
U.S. Department of Health & Human Services —
Background Nocturnin was originally identified by differential display as a circadian clock regulated gene with high expression at night in photoreceptors of the... -
Federal
Evolution and phylogeny of insect endogenous retroviruses
U.S. Department of Health & Human Services —
Background The genome of invertebrates is rich in retroelements which are structurally reminiscent of the retroviruses of vertebrates. Those containing three open... -
Federal
Beta-Adrenergic gene therapy for cardiovascular disease
U.S. Department of Health & Human Services —
Gene therapy using in vivo recombinant adenovirus-mediated gene transfer is an effective technique that offers great potential to improve existing drug treatments for... -
Federal
"In-gel" purified ditags direct synthesis of highly efficient SAGE Libraries
U.S. Department of Health & Human Services —
Background SAGE (serial analysis of gene expression) is a recently developed technique for systematic analysis of eukaryotic transcriptomes. The most critical step in... -
Federal
TheG-308Avariant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution
U.S. Department of Health & Human Services —
Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has... -
Federal
The role of soil factors and leaf protein in the utilization of mopane plants by elephants in northern Botswana
U.S. Department of Health & Human Services —
Background Mopane (Colophospermum mopane) plants form monotypic woodlands that cover extensive areas in northern Botswana. Mopane is also a principal food item in the... -
Federal
1,25-Dihydroxyvitamin D3increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell line
U.S. Department of Health & Human Services —
The active hormonal form of vitamin D (1,25-dihydroxyvitamin D) is the primary regulator of intestinal calcium absorption efficiency. In vitamin D deficiency,... -
Federal
Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation
U.S. Department of Health & Human Services —
Background The peroxisome proliferator-activated receptor α (PPARα) plays an important role in the metabolism of lipoproteins and fatty acids, and seems to protect... -
Federal
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
U.S. Department of Health & Human Services —
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and... -
Federal
Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate
U.S. Department of Health & Human Services —
Background Thiamine diphosphate (ThDP) is the active form of thiamine, and it serves as a cofactor for several enzymes, both cytosolic and mitochondrial. Isolated... -
Federal
Survey of the knowledge, attitude and practice of Nigerian surgery trainees to HIV-infected persons and AIDS patients
U.S. Department of Health & Human Services —
Background The incidence of HIV infection and AIDS is rising in Nigeria. Surgeons are at risk of occupationally acquired infection as a result of intimate contact... -
Federal
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
U.S. Department of Health & Human Services —
Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The... -
Federal
Incomplete gastric metaplasia in children with insulin-dependent diabetes mellitus and celiac disease. An ultrastructural study
U.S. Department of Health & Human Services —
Background The association of insulin-dependent diabetes mellitus (IDDM) and celiac disease (CD) has been widely reported in children but the relationship between the... -
Federal
Blood substitutes: Haemoglobin therapeutics in clinical practice
U.S. Department of Health & Human Services —
Early approaches to the development of oxygen carriers involved the use of stroma-free hemoglobin solutions. These solutions did not require blood typing or...