Search datasets
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Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-,...
Search relevance: 116.71 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:33 PM -
Background Gene targeting would offer a number of advantages over current transposon-based strategies for insect transformation. These include freedom from both position effects...
Search relevance: 116.36 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 08:26 PM -
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly...
Search relevance: 111.65 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:21 PM -
Background: Genome comparisons have revealed major lateral gene transfer between the three primary kingdoms of life - Bacteria, Archaea, and Eukarya. Another important evolutionary...
Search relevance: 111.30 | Views last month: 4 | Catalog Last Checked: September 10, 2026 at 07:41 PM -
The identification of the cystic fibrosis (CF) gene opened the way for gene therapy. In the ten years since then, proof of principle in vitro and then in animal models in vivo has been followed by...
Search relevance: 108.30 | Views last month: 8 | Catalog Last Checked: September 10, 2026 at 07:35 PM -
Background Poly purine.pyrimidine sequences have the potential to adopt intramolecular triplex structures and are overrepresented upstream of genes in eukaryotes. These sequences may...
Search relevance: 105.98 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:01 PM -
Recombinant adenoviruses are straightforward to produce at high titres, have a promiscuous host-range, and, because of their ability to infect nondividing cells, lend themselves to in vivo gene...
Search relevance: 105.71 | Views last month: 3 | Catalog Last Checked: September 10, 2026 at 08:31 PM -
Background As more complete genomes are sequenced, conservation of gene order between different organisms is emerging as an informative property of the genomes. Conservation of gene...
Search relevance: 105.17 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:53 PM -
GEO (Gene Expression Omnibus) is a public functional genomics data repository supporting MIAME-compliant data submissions. There are also tools provided to help users query and download...
Search relevance: 104.65 | Views last month: 16 | Catalog Last Checked: September 10, 2026 at 08:33 PM -
Lipid disorders are associated with atherosclerotic vascular disease, and therapy is associated with a substantial reduction in cardiovascular events. Current approaches to the treatment of lipid...
Search relevance: 104.20 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 07:59 PM -
GENE-TOX provided genetic toxicology (mutagenicity) test data from expert peer review of open scientific literature for more than 3,000 chemicals from the United States Environmental Protection...
Search relevance: 103.40 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:14 PM -
Background Ribosomal proteins are encoded in all genomes of cellular life forms and are, generally, well conserved during evolution. In prokaryotes, the genes for most ribosomal proteins...
Search relevance: 102.71 | Views last month: 13 | Catalog Last Checked: September 10, 2026 at 07:37 PM -
Background Non-allelic homologous recombination between paralogous repeats is increasingly being recognized as a major mechanism causing both pathogenic microdeletions and duplications,...
Search relevance: 102.61 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:19 PM -
Gene counts in brainstem and livers from mice treated for 5 days with oral anatoxin-a (2, 4, and 6mg/kg/day). Tissues were collected 2 weeks after the completion of treatment.
Search relevance: 102.34 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 07:03 PM -
The field of gene therapy for bone and joint disorders has grown considerably over the last two and a half years. Investigators have shown that ex vivo or in vivo gene transfer is highly effective...
Search relevance: 101.58 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:27 PM -
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro model systems, is...
Search relevance: 101.08 | Views last month: 4 | Catalog Last Checked: September 10, 2026 at 06:56 PM -
Background Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution, which suggests a role...
Search relevance: 101.01 | Views last month: 7 | Catalog Last Checked: September 10, 2026 at 08:00 PM -
Background Gene duplications have a major role in the evolution of new biological functions. Theoretical studies often assume that a duplication per se is selectively neutral and that,...
Search relevance: 99.48 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:26 PM -
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is DLG5, a member of the...
Search relevance: 99.20 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:11 PM -
Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12 (12p11.2 - q12)....
Search relevance: 98.56 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:32 PM
