Search datasets
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A collection of R scripts useful for extracting and analyzing adverse outcome pathway network data from the adverse outcome pathway wiki (aopwiki.org). This dataset is associated with the...
Search relevance: 347.39 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 06:55 PM -
The data set provides a set of txt files and cytoscape files that were used to construct the example AOP networks included in the paper. Additionally, a supplementary table file provides all the...
Search relevance: 298.45 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:54 PM -
The EPA has developed the Adverse Outcome Pathway Database (AOP-DB) to better characterize adverse outcomes of toxicological interest that are relevant to human health and the environment. Since...
Search relevance: 298.36 | Views last month: 37 | Catalog Last Checked: September 10, 2026 at 06:57 PM -
In September, 2015, a water sample was collected downstream of a major metropolitan waste water treatment plant that discharges to the South Platte River, Colorado, USA. The grab sample, 1L, was...
Search relevance: 276.24 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:54 PM -
Our ability to conduct whole organism toxicity tests to understand chemical safety has been outpaced by our ability to synthesize new chemicals for a wide variety of commercial applications. ...
Search relevance: 268.72 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 06:53 PM -
"Morshead ML, Jensen KM, Ankley GT, Vliet S, LaLone CA, Aller AV, Watanabe KH, Villeneuve DL. Putative adverse outcome pathway development based on physiological responses of female fathead...
Search relevance: 265.95 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:00 PM -
Previous work identified a ‘cytotoxic burst’ (CTB) phenomenon wherein large numbers of the ToxCast assays begin to respond at or near test chemical concentrations that elicit cytotoxicity, and a...
Search relevance: 265.31 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:54 PM -
Supporting Information for "Jensen, M.A., Blatz, D.J. and LaLone, C.A. (2023), Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study...
Search relevance: 262.88 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 07:00 PM -
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...
Search relevance: 259.06 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 06:56 PM -
Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly...
Search relevance: 257.78 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 06:57 PM -
cell culture information with toxicity and proteomic changes. This dataset is associated with the following publication: VanEmon, J., P. Pan, and F. Van Breukelen. Effects of chlorpyrifos and...
Search relevance: 252.64 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:54 PM -
The majority of this dataset includes the query output from online databases ECOTOX and SeqAPASS used to support the ecological AOP case studies described within the manuscript. The final...
Search relevance: 246.34 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:53 PM -
Datasets used in RD-023418: Adverse Outcome Pathway-Driven Identification of Rat Hepatocarcinogens in Short-Term Assays. This dataset is associated with the following publication: Rooney, J., T....
Search relevance: 219.70 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:55 PM -
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data...
Search relevance: 195.00 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 06:58 PM -
Adequate levels of thyroid hormones (TH) are needed for proper brain development, deficiencies may lead to adverse neurological outcomes in humans and animal models. Environmental chemicals have...
Search relevance: 194.33 | Views last month: 6 | Catalog Last Checked: September 10, 2026 at 06:53 PM -
Metadata for both preliminary and definitive studies, including water quality parameters, experimental takedown data, fin measurements, and RT-PCR data. This dataset is associated with the...
Search relevance: 183.61 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 07:03 PM -
This data set contains R code for a hypothetical exposure model described in the manuscript "A quantitative source-to-outcome case study to demonstrate the integration of human health and...
Search relevance: 171.49 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 06:56 PM -
A set of three proposed "hub" key events were used to link together a series of example adverse outcome pathway (AOP) descriptions that were previously not linked in an AOP network. While there...
Search relevance: 159.01 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 06:55 PM -
This dataset contains ontology terms associated with key events from the AOP-Wiki. This information was used to seed the AOP-Wiki with a carefully selected set of ontology terms prior to opening...
Search relevance: 143.18 | Views last month: 4 | Catalog Last Checked: September 10, 2026 at 06:54 PM -
A publised mansucript describing a quantitative adverse outcome pathway (qAOP) and its relevance to risk assessment. This dataset is not publicly accessible because: This work describes...
Search relevance: 136.88 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 06:53 PM
