Search datasets
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This is a new, open, and transparent database of toxicokinetic data supporting EPA decision making. The database has already become the basis of research efforts within EPA to improve HTTK...
Search relevance: 1.00 | Views last month: 30 | Catalog Last Checked: April 21, 2026 at 08:00 PM -
Table S1: Tox21 IDs mapped to NCGC IDs, PubChem IDs, and DSSTox IDs, and indicating NCATS, NTP and EPA partner library associations (date stamped February 24, 2020). Table S2: DSSTox TOX21SL list...
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Japanese quail (Coturnix japonica) were orally dosed with pesticide-treated or control-untreated wheat seeds. Pesticide treated wheat seeds were analytically verified for active ingredients of...
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Background It is generally assumed that the tissue exchange of antibiotics is flow limited (complete equilibration between the capillary and the tissue water). This assumption may not be...
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In this study, a major effort was undertaken to compile a large genotoxicity dataset (54,805 records for 9299 substances) from several public sources (e.g., TOXNET, COSMOS, eChemPortal). The names...
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Anatoxin levels in mouse tissues after a single exposure and collected at various timepoints
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: April 21, 2026 at 08:08 PM -
Background This paper assess the relationship between the quantity of three anti-seizure medications in hair and the color of the analyzed hair, while controlling for the effects of...
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File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for...
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Here are all of the data files used for this manuscript. Please note that this is all published data. Imran Shah 1.1060+ Chemicals and Chemical controls 2. Chemical descriptors (chm): 2048 Morgan...
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Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively...
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Read-across (RAX) is a widely used data gap filling approach and the authors have developed a data-driven tool, called GenRA, to support expert-driven RAX. This work describes a stand-alone Python...
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Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific...
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Acute rat oral toxicity lethality data files, processed prediction files from 2 expert systems. This dataset is associated with the following publication: Nelms, M., A. Karmaus, and G....
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An effort was made to derive new inhalation TTC values using the EPA’s Toxicity Values database, ToxValDB. A total of 4703 substances captured in ToxValDB were assigned into their respective TTC...
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Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for...
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This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for...
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Mouse assays. This dataset is associated with the following publication: Diamond, G., K. Bradham, and D. Thomas. Evaluating the Mouse Model for Estimation of Arsenic Bioavailability: Comparison...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: April 21, 2026 at 08:03 PM -
Pharmacology of the critically ill
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 07, 2025 at 09:12 AM
