Model Code Associated with "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors"
This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors." The model code is written in R with a .model file written in the MCSim language. The inhalation pharmacokinetic model builds on a previous publication of Bernstein et al., "A Model Template Approach for Rapid Evaluation and Application of Physiologically Based Pharmacokinetic Models for Use in Human Health Risk Assessments: A Case Study on Per- and Polyfluoroalkyl Substances" https://doi.org/10.1093/toxsci/kfab063
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Michael Dzierlenga", "hasEmail": "mailto:dzierlenga.michael@epa.gov" } |
| description | This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors." The model code is written in R with a .model file written in the MCSim language. The inhalation pharmacokinetic model builds on a previous publication of Bernstein et al., "A Model Template Approach for Rapid Evaluation and Application of Physiologically Based Pharmacokinetic Models for Use in Human Health Risk Assessments: A Case Study on Per- and Polyfluoroalkyl Substances" https://doi.org/10.1093/toxsci/kfab063 |
| distribution |
[ { "title": "PFAS_inhalation_PBPK_template.zip", "mediaType": "application/zip", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532470/PFAS_inhalation_PBPK_template.zip" } ] |
| identifier | https://doi.org/10.23719/1532470 |
| keyword |
[ "PFAS", "Risk Assessment", "inhalation", "pharmacokinetics", "toxicokinetics" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2025-08-21 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
null
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| rights |
null
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| title | Model Code Associated with "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors" |
