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Asthma and PM
PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air pollution used... -
Losartan and diabetic nephropathy: commentaries on the RENAAL study
The RENAAL (Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan) study is a multinational, double-blind, randomized, placebo controlled trial which was... -
Modeling of failure mode in knee ligaments depending on the strain rate
Background The failure mechanism of the knee ligament (bone-ligament-bone complex) at different strain rates is an important subject in the biomechanics of the knee. This study... -
Is endosonography an effective method for detection and local staging of the ampullary carcinoma? A prospective study
Background The relatively rare carcinoma of the ampulla of Vater is a neoplasia with a good prognosis compared to pancreatic cancer. Preoperative staging is important in... -
Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies
Background We investigated fetal and total DNA levels in maternal plasma in patients bearing fetuses affected with Down syndrome in comparison to controls carrying fetuses with... -
Cardiac rehabilitation: a comprehensive review
Cardiac rehabilitation (CR) is a commonly used treatment for men and women with cardiovascular disease. To date, no single study has conclusively demonstrated a comprehensive... -
A prospective study of rural drinking water quality and acute gastrointestinal illness
Background This study examined the relationship between the bacteriological contamination of drinking water from private wells and acute gastrointestinal illness (AGII), using... -
Preconceptional factors associated with very low birthweight delivery in East and West Berlin: a case control study
Background Very low birthweight, i.e. a birthweight < 1500 g, is among the strongest determinants of infant mortality and childhood morbidity. To develop primary prevention... -
The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis will be based... -
Continuous haemofiltration in the intensive care unit
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU). Since that... -
Use of intravenous antiarrhythmics to identify concealed Brugada syndrome
Cardiology has recently witnessed the production of an overwhelming amount of data through the advances made in genetics and molecular biology research. Understanding of... -
Genetic polymorphisms in lung disease: bandwagon or breakthrough?
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define... -
Antenatal screening and its possible meaning from unborn baby's perspective
In recent decades antenatal screening has become one of the most routine procedure of pregnancy-follow up and the subject of hot debate in bioethics circles. In this paper the... -
Sex differences in risk factors for coronary heart disease: a study in a Brazilian population
Background In Brazil coronary heart disease (CHD) constitutes the most important cause of death in both sexes in all the regions of the country and interestingly, the difference... -
Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports
Background Evaluation of company clinical trial reports could provide information for meta-analysis at the commercial introduction of a new technology. Methods Clinical trial... -
Plasma colloid osmotic pressure in healthy infants
Background The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants beyond the... -
Debate: The potential role of estrogen in the prevention of heart disease in women after menopause
Large numbers of observational studies have described a decrease in the incidence of cardiovascular disease in women taking hormone replacement therapy (HRT). The potential... -
Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to limited... -
Bone mineral density and the subsequent risk of cancer in the NHANES I follow-up cohort
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with... -
To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?
Background Patients with Alzheimer's disease experience a progressive loss of cognitive function, and the ability to independently perform activities of daily life. Sometimes a...
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