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Data from: The Effect of Sodium Benzoate on the Gut Microbiome Across Age Groups
An ex vivo study of the effects on the human gut microbiota of the food additive sodium butyrate (SB) at a concentration of 3.5 g/L. Incubations were performed on fecal slurries from 24 donors spanning 3 age groups (toddler, adults 25-40 years, adults 60+ years). Samples include initial time point (pre-incubation) and untreated controls and treated samples after 24 hours of incubation. Data collected include: shotgun metagenomic DNA sequencing, biomass (cell counts), short-chain fatty acid concentrations, gas and pH. These measures and donor metadata are in this dataset with sample IDs linking to sequencing data housed in the NCBI Sequence Read Archive associated with BioProject PRJNA1160256.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "005:18" ] |
| contactPoint |
{ "fn": "Narrowe, Adrienne B.", "hasEmail": "mailto:adrienne.narrowe@usda.gov" } |
| description | <p dir="ltr">An<i> ex vivo</i> study of the effects on the human gut microbiota of the food additive sodium butyrate (SB) at a concentration of 3.5 g/L. Incubations were performed on fecal slurries from 24 donors spanning 3 age groups (toddler, adults 25-40 years, adults 60+ years). Samples include initial time point (pre-incubation) and untreated controls and treated samples after 24 hours of incubation. Data collected include: shotgun metagenomic DNA sequencing, biomass (cell counts), short-chain fatty acid concentrations, gas and pH. These measures and donor metadata are in this dataset with sample IDs linking to sequencing data housed in the NCBI Sequence Read Archive associated with BioProject PRJNA1160256.</p> |
| distribution |
[ { "@type": "dcat:Distribution", "title": "SB_metadata.csv", "format": "csv", "mediaType": "text/csv", "downloadURL": "https://ndownloader.figshare.com/files/65153523" } ] |
| identifier | 10.15482/USDA.ADC/32409090.v1 |
| keyword |
[ "Sodium Benzoate", "food additives", "food preservatives", "gut microbiome", "metagenomics" ] |
| license | https://creativecommons.org/publicdomain/zero/1.0/ |
| modified | 2026-06-11 |
| programCode |
[ "005:040" ] |
| publisher |
{ "name": "Agricultural Research Service", "@type": "org:Organization" } |
| temporal | 2023-04-17/2023-09-18 |
| title | Data from: The Effect of Sodium Benzoate on the Gut Microbiome Across Age Groups |
