Data from: An in vitro analysis of how lactose modifies the gut microbiota structure and function of adults in a donor-independent manner
The impact of lactose on the gut microbiota of healthy adults was examined, using a short-term, in vitro strategy where fecal samples harvested from 18 donors were cultured anaerobically with and without lactose. Donors represented 3 adult age groups. Data collected include: amplicon sequencing of the V1-V2 regions of the 16S rRNA gene (available in the NCBI Sequence Read Archive associated with BioProject PRJNA883645: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883645), RT-qPCR of Bifidobacterium 16S rRNA genes, and short-chain fatty acid concentrations.
Resources in this dataset:
Resource Title: lactose sample attributes
File Name: lactose_sample_metadata.csv
Resource Title: lactose SCFA, pH, and gas production data
File Name: lactose_SCFA_data.csv
Resource Title: Total bacterial and Bifidobacterium genus qPCR
File Name: lactose_qPCR_all_bacteria_and_bifido.csv
Resources
3 resources available
-
lactose_sample_metadata.csv
CSV -
lactose_SCFA_data.csv
CSV -
lactose_qPCR_all_bacteria_and_bifido.csv
CSV
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "005:18" ] |
| contactPoint |
{ "fn": "Narrowe, Adrienne", "hasEmail": "mailto:adrienne.narrowe@usda.gov" } |
| description | <p>The impact of lactose on the gut microbiota of healthy adults was examined, using a short-term, in vitro strategy where fecal samples harvested from 18 donors were cultured anaerobically with and without lactose. Donors represented 3 adult age groups. Data collected include: amplicon sequencing of the V1-V2 regions of the 16S rRNA gene (available in the NCBI Sequence Read Archive associated with BioProject PRJNA883645: <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883645">https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883645</a>), RT-qPCR of Bifidobacterium 16S rRNA genes, and short-chain fatty acid concentrations. </p> <p>Resources in this dataset:</p> <ul> <li> <p>Resource Title: lactose sample attributes File Name: lactose_sample_metadata.csv</p> </li> <li> <p>Resource Title: lactose SCFA, pH, and gas production data File Name: lactose_SCFA_data.csv</p> </li> <li> <p>Resource Title: Total bacterial and Bifidobacterium genus qPCR File Name: lactose_qPCR_all_bacteria_and_bifido.csv</p> </li> </ul> |
| distribution |
[ { "@type": "dcat:Distribution", "title": "lactose_sample_metadata.csv", "format": "csv", "mediaType": "text/plain", "downloadURL": "https://ndownloader.figshare.com/files/43734918" }, { "@type": "dcat:Distribution", "title": "lactose_SCFA_data.csv", "format": "csv", "mediaType": "text/plain", "downloadURL": "https://ndownloader.figshare.com/files/43734921" }, { "@type": "dcat:Distribution", "title": "lactose_qPCR_all_bacteria_and_bifido.csv", "format": "csv", "mediaType": "text/plain", "downloadURL": "https://ndownloader.figshare.com/files/43734930" } ] |
| identifier | 10.15482/USDA.ADC/1529150 |
| keyword |
[ "16S rRNA sequence data", "ARS", "NP306", "data.gov", "lactose", "short chain fatty acids" ] |
| license | https://creativecommons.org/licenses/by/4.0/ |
| modified | 2025-11-21 |
| programCode |
[ "005:040" ] |
| publisher |
{ "name": "Agricultural Research Service", "@type": "org:Organization" } |
| spatial |
"{"type": "Point", "coordinates": [-75.187092456102, 40.078126249741]}"
|
| temporal | 2021-06-01/2021-06-01 |
| title | Data from: An in vitro analysis of how lactose modifies the gut microbiota structure and function of adults in a donor-independent manner |
