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Federal
A functional update of the
U.S. Department of Health & Human Services —
Background Since the genome of Escherichia coli K-12 was initially annotated in 1997, additional functional information based on biological characterization and... -
Federal
Research Article: Genome Biology
U.S. Department of Health & Human Services —
Background Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous... -
Federal
Towards understanding the first genome sequence of a crenarchaeon by genome annotation using clusters of orthologous groups of proteins (COGs)
U.S. Department of Health & Human Services —
Background: Standard archival sequence databases have not been designed as tools for genome annotation and are far from being optimal for this purpose. We used the...