58 datasets found
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Federal
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [sounding rocket]
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
Federal
Spaceflight effects on the mouse retina: Histological gene expression and epigenetic changes after flight on STS-135
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Gene expression response to simulated gravity and hypergravity in human T cells
National Aeronautics and Space Administration —
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
Federal
Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer
National Aeronautics and Space Administration —
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in... -
Federal
Dynamic gene expression response to altered gravity in human T cells (parabolic flight)
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
Dynamic gene expression response to altered gravity in human T cells (sounding rocket flight)
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice
National Aeronautics and Space Administration —
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in... -
Federal
Global DNA methylation profiling of radiation-induced rat mammary carcinomas
National Aeronautics and Space Administration —
To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat... -
Federal
Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles
National Aeronautics and Space Administration —
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls.... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Expression Data from International C. elegans Experiment 1st (ICE-FIRST)
National Aeronautics and Space Administration —
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray (Agilent). Overall design: Mix staged C. elegans N2 was... -
Federal
Environmental and facility conditions promote singular gravity responses of transcriptome during Drosophila metamorphosis
National Aeronautics and Space Administration —
Genome-wide transcriptional profiling showed that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene... -
Federal
Synergistic effects of space radiation and microgravity (miRNA WT and dys-mutant)
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
Global Identification of Noncoding RNAs in S. cerevisiae
National Aeronautics and Space Administration —
Genome-wide detection of novel non-coding RNAs in S. cerevisiae by modulating an RNase P pathway through the depletion of a component RPP1. Nearly 400,000 36-mer... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Hindlimb suspension and reloading study
National Aeronautics and Space Administration —
Analysis of effect of hindlimb suspension and reloading on C57Bl/6 mouse soleus muscle. Experimental groups examined: -Control mice 14 days -Hindlimb suspension for 7... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 4 days)
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 4 days in the Japanese...
58 datasets found